Ezetimibe Impurity 35 CAS 70627-52-0
| CAS No. | 70627-52-0 |
| Molecular Formula | C20H16FNO |
| Molecular Weight | 305.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ezetimibe Impurity 35 (CAS 70627-52-0) is a certified pharmaceutical impurity reference standard with the molecular formula C20H16FNO and a molecular weight of 305.35 g/mol.
Ezetimibe Impurity 35 (C20H16FNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ezetimibe Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H16FNO |
| Molecular Weight | 305.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 145 (Z-Isomer) (CAS CATO-C4X-1098145)
- Ezetimibe Impurity 98 (CAS CATO-C4X-109898)
- Ezetimibe Impurity 114 (CAS CATO-C4X-1098114)
- Ezetimibe Impurity 28 (CAS CATO-C4X-109828)
- Ezetimibe Impurity 62 (CAS 1618657-31-0)
- Ezetimibe Impurity N49 (CAS 1056188-47-6)
- Ezetimibe Impurity 95 (CAS CATO-C4X-109895)
- Ezetimibe Impurity 76 (CAS CATO-C4X-109876)
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- 2,5-Dichlorothiazolo[5,4-d]thiazole (CAS 50616-95-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com