(3-Bromo-2-fluorophenyl)trimethylsilane CAS 161957-53-5
| CAS No. | 161957-53-5 |
| Molecular Formula | C9H12BrFSi |
| Molecular Weight | 247.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3-Bromo-2-fluorophenyl)trimethylsilane is closely related to fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (3-Bromo-2-fluorophenyl)trimethylsilane (CAS 161957-53-5), a certified reference material (molecular formula C9H12BrFSi, MW 247.18 g/mol) for analytical method development and quality control.
Owing to fluorine/bromine substitution, (3-Bromo-2-fluorophenyl)trimethylsilane is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 247.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12BrFSi |
| Molecular Weight | 247.18 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F/Br-containing |
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Recommended Standards
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- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
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