6-Chloro-2-fluoro-3-hydroxybenzaldehyde CAS 1704729-56-5
| CAS No. | 1704729-56-5 |
| Molecular Formula | C7H4ClFO2 |
| Molecular Weight | 174.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 6-Chloro-2-fluoro-3-hydroxybenzaldehyde (CAS 1704729-56-5), a certified reference material (molecular formula C7H4ClFO2, MW 174.56 g/mol) for analytical method development and quality control.
The molecular framework of 6-Chloro-2-fluoro-3-hydroxybenzaldehyde (C7H4ClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 6-Chloro-2-fluoro-3-hydroxybenzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClFO2 |
| Molecular Weight | 174.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-3-fluorobenzoic Acid (CAS 102940-86-3)
- 2-Chloro-5-fluoro-4-hydroxybenzaldehyde (CAS 1036383-27-3)
- 2-Chloro-6-fluoro-3-hydroxybenzaldehyde (CAS 1083103-41-6)
- 3-Chloro-6-fluoro-2-hydroxybenzaldehyde (CAS 1185112-08-6)
- 4-Chloro-5-fluoro-2-hydroxybenzaldehyde (CAS 1205551-36-5)
- 2-Chloro-3-fluoro-6-hydroxybenzaldehyde (CAS 1263378-00-2)
- 1-(6-Chloro-5-fluoro-4-pyrimidinyl)ethanone (CAS 1289559-80-3)
- 2-chloro-3-fluoropyridine-4-carboxamide (CAS 1378654-14-8)
Recommended Standards
- 3-Chloro-2-fluorobenzoic Acid (CAS 161957-55-7)
- 4-Chloro-5-fluoronicotinamide (CAS 1706432-64-5)
- 4-Chloro-3-fluoro-2-hydroxybenzaldehyde (CAS 1427431-22-8)
- 2-Chloro-4-fluoronicotinamide (CAS 1823944-18-8)
- (R)-Ethyl 1-benzylpyrrolidine-2-carboxylate (CAS 172478-10-3)
- 5-Amino-1-(2-chloro-4-fluoro-5-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1159678-57-5)
- [(5,6,7,8-tetrahydronaphthalen-2-ylsulfonyl)amino]acetic acid (CAS 790681-76-4)
- 5-Acetyl-6-phenyl-2-sulfanylpyridine-3-carbonitrile (CAS 851722-01-5)
- N-((1H-indol-3-yl)methyl)-2-phenylethan-1-amine (CAS 256440-49-0)
- 4-amino-8-methyl-1,2-dihydroquinoline-2-thione (CAS 360078-60-0)
- Propyl 4-(3-bromo-4-hydroxy-5-methoxyphenyl)-7-(3,4-dimethoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 494193-83-8)
- Ethyl 8-hydroxyquinoline-7-carboxylate (CAS 55477-70-8)
- 9-Methyl-9h-carbazole-3,6-dicarbaldehyde (CAS 29377-72-8)
- Exenatide (CAS 141758-74-9)
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