Atazanavir impurity 19 CAS 156474-21-4
| CAS No. | 156474-21-4 |
| Molecular Formula | C15H21NO3 |
| Molecular Weight | 263.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Atazanavir impurity 19.
CATO supplies Atazanavir impurity 19 (CAS 156474-21-4), a pharmacopoeial impurity reference standard (molecular formula C15H21NO3, MW 263.33 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Atazanavir impurity 19 (C15H21NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Atazanavir impurity 19 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H21NO3 |
| Molecular Weight | 263.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Nitrogen Atoms | 1 |
Related Atazanavir Standards
- Atazanavir Impurity N1 (Relative stereochemistry) (CAS 98818-34-9)
- Atazanavir Impurity 10 (CAS 98737-29-2)
- Atazanavir Impurity 11 (CAS 156474-22-5)
- Atazanavir Impurity 13 (CAS 98760-08-8)
- Atazanavir Impurity 23 (CAS 149451-80-9)
- Atazanavir Impurity 12 (CAS 198904-84-6)
- Atazanavir Impurity 14 (CAS 102123-74-0)
- Atazanavir Impurity 12 (CAS 162536-40-5)
Recommended Standards
- Esmolol Impurity 71 (CAS CATO-C4X-189171)
- Erdosteine Methyl Ester (CAS 1667709-77-4)
- Pethidine Impurity 12 (CAS 13147-07-4)
- Venlafaxine Impurity 83 (CAS CATO-C4X-143483)
- Otilonium Bromide Impurity 6 (CAS 51444-79-2)
- Difenidol Impurity 8 HCl (CAS 17874-62-3)
- Vonoprazan Impurity 48 (CAS CATO-C4X-1020248)
- 3-(3-Chlorophenyl)-5-(cinnamylthio)-4H-1,2,4-triazol-4-amine (CAS 578698-78-9)
- 4-Chloro-5-(2-fluoropyridin-3-yl)-1H-pyrrole-3-carbaldehyde (CAS 928325-27-3)
- 1-(2-Fluoro-3-hydroxyphenyl)cyclopentane-1-carbonitrile (CAS 1881322-18-4)
- 5-Amino-1H-pyrrole-2-carbaldehyde (CAS 57500-59-1)
- 4-Chloro-7-methoxyindolin-2-one (CAS 1260674-54-1)
- 7-(3,4-Dichlorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazine (CAS 73214-12-7)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
Why CATO?
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