Linagliptin Impurity 36 CAS 1638744-06-5
| CAS No. | 1638744-06-5 |
| Molecular Formula | C25H29BrN8O2 |
| Molecular Weight | 553.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Linagliptin Impurity 36 (CAS 1638744-06-5), a pharmacopoeial impurity reference standard (molecular formula C25H29BrN8O2, MW 553.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Linagliptin Impurity 36 (C25H29BrN8O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 553.45 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Linagliptin Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H29BrN8O2 |
| Molecular Weight | 553.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 8 |
Related Linagliptin Standards
- Linagliptin impurity N2 (CAS 1446263-39-3)
- Linagliptin Impurity N13 (CAS 2138392-83-1)
- Linagliptin Impurity 134 (CAS 2469626-53-5)
- Linagliptin Impurity 160 (CAS CATO-C4X-1101160)
- Linagliptin Impurity 77 (CAS 1673546-62-7)
- Linagliptin Impurity 123 (CAS CATO-C4X-1101123)
- Linagliptin impurity 143 (CAS 2517759-32-7)
- Linagliptin Impurity 159 (CAS CATO-C4X-1101159)
Recommended Standards
- Cot inhibitor-1 (CAS 915365-57-0)
- 3-Bromo-9-(3-(4,6-diphenyl-1,3,5-triazin-2-yl)phenyl)-9H-carbazole (CAS 1266389-19-8)
- Perfluorophenyl N-Fmoc-D-phenylalaninate (CAS 159505-85-8)
- Dotinurad Impurity 201 (CAS CATO-C4X-2494201)
- Azithromycin Impurity 47 (CAS CATO-C4X-100347)
- Oclacitinib impurity 17 (CAS CATO-C4X-301817)
- Papaverine impurity 19 HCl (CAS CATO-C4X-206719)
- 1,4-Dihydropyridine-4-carboxylic acid (CAS 182301-56-0)
- Methyl 2-Amino-6-fluorobenzoate (CAS 86505-94-4)
- Iguratimod Impurity 121 (CAS CATO-C4X-1826121)
- Isocyanatocyclododecane (CAS 480439-08-5)
- Methyl 2-(3-iodophenyl)acetate (CAS 502649-73-2)
- 2-Fluoro-6-isopropoxyaniline (CAS 1184820-85-6)
- Semaglutide impurity 92 (CAS CATO-C4X-222692)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com