Linagliptin Impurity N13 CAS 2138392-83-1
| CAS No. | 2138392-83-1 |
| Molecular Formula | C26H21BrN8O2 |
| Molecular Weight | 557.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Linagliptin Impurity N13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Linagliptin Impurity N13 (CAS 2138392-83-1), a pharmacopoeial impurity reference standard (molecular formula C26H21BrN8O2, MW 557.41 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Linagliptin Impurity N13 (C26H21BrN8O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H21BrN8O2 |
| Molecular Weight | 557.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 8 |
Related Linagliptin Standards
- Linagliptin impurity N2 (CAS 1446263-39-3)
- Linagliptin Impurity 36 (CAS 1638744-06-5)
- Linagliptin Impurity 134 (CAS 2469626-53-5)
- Linagliptin Impurity 160 (CAS CATO-C4X-1101160)
- Linagliptin Impurity 77 (CAS 1673546-62-7)
- Linagliptin Impurity 123 (CAS CATO-C4X-1101123)
- Linagliptin impurity 143 (CAS 2517759-32-7)
- Linagliptin Impurity 159 (CAS CATO-C4X-1101159)
Recommended Standards
- SGI-110, 96% (CAS 929901-49-5)
- 2-((N-(2,4-dichloro-5-(2-methoxyethoxy)phenyl)-4-methoxyphenyl)sulfonamido)-N-(4-fluorophenyl)acetamide (CAS 338967-85-4)
- Crisaborole Impurity 29 (CAS CATO-C4X-202129)
- tert-Butyl (3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)-7-iodo-1,2,3a,4,5,9b-hexahydro-3H-benzo[e]indole-3-carboxylate (CAS 2041843-03-0)
- N-Nitroso Relebactam Impurity 51 (CAS CATO-C4X-214451)
- Iomeprol Impurity 2 (CAS 104517-95-5)
- Imidafenacin Impurity N1 (CAS 562091-56-9)
- Potassium (3-(cyanomethyl)phenyl)trifluoroborate (CAS 1073468-32-2)
- 2-(5-Bromofuran-2-yl)-5-hydrazinyloxazole-4-carbonitrile (CAS 1353501-73-1)
- 2-Cyclopropoxy-N-methyl-5-(trifluoromethyl)benzamide (CAS 1243402-66-5)
- Tert-butyl n6-((benzyloxy)carbonyl)lysinate hydrochloride (CAS 1396966-35-0)
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Why CATO?
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