Tryptophan EP Impurity J CAS 164068-19-3
| CAS No. | 164068-19-3 |
| Molecular Formula | C22H23N3O4 |
| Molecular Weight | 393.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tryptophan EP Impurity J (CAS 164068-19-3) is a certified pharmaceutical impurity reference standard with the molecular formula C22H23N3O4 and a molecular weight of 393.44 g/mol.
Structurally, Tryptophan EP Impurity J (C22H23N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 393.44 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tryptophan EP Impurity J meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H23N3O4 |
| Molecular Weight | 393.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 3 |
Related Tryptophan Standards
- Tryptophan impurity 41 (CAS CATO-C4X-137341)
- Tryptophan impurity 42 (CAS CATO-C4X-137342)
- Tryptophan impurity 39 (CAS CATO-C4X-137339)
- Tryptophan impurity 40 (CAS CATO-C4X-137340)
- Tryptophan Impurity 15 (CAS 180509-18-6)
- Tryptophan Impurity 52 (CAS CATO-C4X-137352)
- Tryptophan EP Impurity A (CAS 132685-02-0)
- Tryptophan impurity 37 (CAS CATO-C4X-137337)
Recommended Standards
- Erlotinib Impurity 96 (CAS CATO-C4X-106996)
- Valdecoxib Impurity 1 (CAS CATO-C4X-14511)
- Erlotinib Impurity 55 (CAS 2410548-57-9)
- N-Nitroso Indacaterol Mono Ethyl Impurity 65 (CAS CATO-C4X-150065)
- Doxylamine EP Impurity B (CAS 19490-92-7)
- Cefadroxil Impurity 31 (CAS CATO-C4X-122431)
- Pethidine impurity 8 (CAS CATO-C4X-22328)
- N-(4-Fluorophenyl)-2-(2-oxobutoxy)pyrimidine-5-carboxamide (CAS 923292-38-0)
- Diethyl(4-(ethylamino)phenyl)phosphine oxide (CAS 87981-13-3)
- 8-Chloro-2-phenylimidazo[1,2-a]pyrazine (CAS 1447607-84-2)
- Iodixanol USP Related Compound D (CAS 89797-00-2)
- 4-(Azetidin-3-yl)pyrimidine hydrochloride (CAS 1236861-79-2)
- 5-(Methoxymethyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)furan-2-carboxamide (CAS 881933-24-0)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com