Tryptophan impurity 42 CAS CATO-C4X-137342
| CAS No. | CATO-C4X-137342 |
| Molecular Formula | C18H20N4O6 |
| Molecular Weight | 388.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tryptophan impurity 42 (C18H20N4O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Tryptophan impurity 42 (CAS CATO-C4X-137342) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20N4O6 and a molecular weight of 388.37 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tryptophan impurity 42 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20N4O6 |
| Molecular Weight | 388.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Tryptophan Standards
- Tryptophan impurity 41 (CAS CATO-C4X-137341)
- Tryptophan EP Impurity J (CAS 164068-19-3)
- Tryptophan Impurity 15 (CAS 180509-18-6)
- Tryptophan impurity 39 (CAS CATO-C4X-137339)
- Tryptophan impurity 40 (CAS CATO-C4X-137340)
- Tryptophan EP Impurity L (CAS 287170-99-4)
- Tryptophan Impurity 52 (CAS CATO-C4X-137352)
- Tryptophan EP Impurity A (CAS 132685-02-0)
Recommended Standards
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- Dexrazoxane Impurity 35 (CAS CATO-C4X-202035)
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- S-Ethyl 2-(5-ethoxytetrahydrofuran-2-yl)ethanethioate (CAS 475275-15-1)
- Boc-Arg(Pbf)-Oet (CAS CATO-CPTD788832)
- 1-(3-Bromo-4-methoxyphenyl)ethan-1-amine (CAS 634150-47-3)
- Roxadustat Impurity 47 (CAS CATO-C4X-221347)
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