3-Bromo-4'-chloro-1,1'-biphenyl CAS 164334-69-4
| CAS No. | 164334-69-4 |
| Molecular Formula | C12H8BrCl |
| Molecular Weight | 267.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Bromo-4'-chloro-1,1'-biphenyl.
CATO supplies 3-Bromo-4'-chloro-1,1'-biphenyl (CAS 164334-69-4), a certified reference material (molecular formula C12H8BrCl, MW 267.55 g/mol) for analytical method development and quality control.
The molecular framework of 3-Bromo-4'-chloro-1,1'-biphenyl (C12H8BrCl) is characterized by chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8BrCl |
| Molecular Weight | 267.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
- 2-Bromo-2'-chloro-1,1'-biphenyl (CAS 107208-70-8)
- 3-Bromo-5-chloro-1,1'-biphenyl (CAS 126866-35-1)
- 2-Bromo-3'-chloro-1,1'-biphenyl (CAS 154407-17-7)
- 2-Bromo-4'-chloro-1,1'-biphenyl (CAS 179526-95-5)
- 2-Bromo-4-chloro-1,1'-biphenyl (CAS 1805001-22-2)
- 2-Bromo-5-chloro-1,1'-biphenyl (CAS 1936711-65-7)
- 3-Bromo-3'-chloro-1,1'-biphenyl (CAS 844856-42-4)
- 4'-Bromo-2-chloro-1,1'-biphenyl (CAS 39802-88-5)
Recommended Standards
- Nintedanib impurity 181 (CAS CATO-C4X-1814181)
- 2,2,2-Trichloro-1-phenylethyl acetate (CAS 90-17-5)
- 2-(2,4-Dichlorophenoxy)butanoyl chloride (CAS 854874-29-6)
- 4'-Bromo-3-chloro-1,1'-biphenyl (CAS 91354-09-5)
- 8-Chloroadenosine (CAS 34408-14-5)
- N-Acetyl-4-hydroxy-L-proline (cis- and trans- mixture) (CAS 926905-71-7)
- p-Nitrophenyl Penta-N-acetyl-β-chitopentaoside (CAS 114882-45-0)
- N-(1-Isobutyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-sulfonamide (CAS 941955-34-6)
- Ethyl 4-(1,3-dioxoisoindolin-2-yl)benzoate (CAS 130872-52-5)
- 3-(4-Aminophenyl)-N-ethylbenzamide (CAS 1345471-45-5)
- Adenosine 5'-triphosphate disodium salt (CAS 987-65-5)
- (1-(3-Methoxybenzyl)cyclopropyl)methanol (CAS 1486641-15-9)
- 5-(chlorosulfonyl)-2-ethylbenzoic acid (CAS 866358-16-9)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com