Ticagrelor Impurity 58 CAS 1643378-48-6
| CAS No. | 1643378-48-6 |
| Molecular Formula | C23H28F2N6O4S |
| Molecular Weight | 522.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ticagrelor Impurity 58 (C23H28F2N6O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Ticagrelor Impurity 58 (CAS 1643378-48-6), a pharmacopoeial impurity reference standard (molecular formula C23H28F2N6O4S, MW 522.57 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ticagrelor Impurity 58 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H28F2N6O4S |
| Molecular Weight | 522.57 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 14 (CAS 1808068-84-9)
- Ticagrelor (CAS 274693-27-5)
- Ticagrelor Impurity 1 (CAS 2096989-55-6)
- Ticagrelor Impurity 182 (CAS CATO-C4X-1093182)
- Ticagrelor Impurity 183 (CAS CATO-C4X-1093183)
- Ticagrelor Impurity 189 (CAS CATO-C4X-1093189)
- Ticagrelor Impurity 190 (CAS 2880337-24-4)
- Ticagrelor Impurity 191 (CAS CATO-C4X-1093191)
Recommended Standards
- Ticagrelor EP Impurity B (CAS 1788033-05-5)
- Ticagrelor Impurity 64 (CAS 2435586-40-4)
- Ticagrelor Impurity 36 (CAS CATO-C4X-109336)
- Ticagrelor Impurity 89 (CAS 2056269-94-2)
- Milrinone Impurity 26 (CAS CATO-C4X-109126)
- Ethacridine Lactate Impurity 8 (CAS 328258-90-8)
- Cefcapene Impurity 68 (CAS CATO-C4X-182468)
- Ethyl 5-(2-(methylthio)phenyl)-5-oxopentanoate (CAS 951888-98-5)
- 2-(5-Bromofuran-2-yl)-4-chloro-6-methylpyrimidine (CAS 1155156-32-3)
- 2-Bromo-4-chloro-3,5,6-trifluorobenzonitrile (CAS 1889491-46-6)
- 5-(Pyridin-4-yl)-1H-indole (CAS 90679-35-9)
- 4-(5-Methyl-2-nitrophenoxy)piperidine (CAS 1285595-56-3)
- 1-(3-Chloropyridin-2-yl)cyclopropan-1-amine (CAS 1260913-26-5)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com