Ticagrelor Impurity 64 CAS 2435586-40-4
| CAS No. | 2435586-40-4 |
| Molecular Formula | C23H28F2N6O4S |
| Molecular Weight | 522.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 522.57 g/mol gives Ticagrelor Impurity 64 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Ticagrelor Impurity 64 (CAS 2435586-40-4, C23H28F2N6O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ticagrelor Impurity 64 (C23H28F2N6O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H28F2N6O4S |
| Molecular Weight | 522.57 g/mol |
| Purity | >95.0% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 14 (CAS 1808068-84-9)
- Ticagrelor (CAS 274693-27-5)
- Ticagrelor Impurity 1 (CAS 2096989-55-6)
- Ticagrelor Impurity 182 (CAS CATO-C4X-1093182)
- Ticagrelor Impurity 183 (CAS CATO-C4X-1093183)
- Ticagrelor Impurity 189 (CAS CATO-C4X-1093189)
- Ticagrelor Impurity 190 (CAS 2880337-24-4)
- Ticagrelor Impurity 191 (CAS CATO-C4X-1093191)
Recommended Standards
- Ticagrelor Impurity 58 (CAS 1643378-48-6)
- Ticagrelor Impurity 89 (CAS 2056269-94-2)
- Ticagrelor EP Impurity B (CAS 1788033-05-5)
- Paclitaxel Impurity 31 (CAS 171926-87-7)
- Dapoxetine Impurity N1 (CAS 82769-76-4)
- Nicardipine Impurity 68 (CAS CATO-C4X-171068)
- Fingolimod Impurity 30 (CAS CATO-C4X-164630)
- (S)-1-(3-bromophenyl)butan-1-amine (CAS 1391536-26-7)
- 1-(Bromomethyl)-2-(4-methylphenoxy)benzene (CAS 1427460-35-2)
- n-[2-(benzyloxy)phenyl]acetamide (CAS 34288-19-2)
- 4'-(Acetyloxy)-[1,1'-biphenyl]-3-carboxylic acid (CAS 300675-38-1)
- VU 0364739 hydrochloride (CAS 1244640-48-9)
- n-(2,4-Dimethylbenzyl)-3-methoxypropan-1-amine (CAS 1038279-85-4)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
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