1-Chloro-2-(trifluoromethoxy)ethane CAS 1645-95-0
| CAS No. | 1645-95-0 |
| Molecular Formula | C3H4ClF3O |
| Molecular Weight | 148.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Chloro-2-(trifluoromethoxy)ethane.
CATO supplies 1-Chloro-2-(trifluoromethoxy)ethane (CAS 1645-95-0), a certified reference material (molecular formula C3H4ClF3O, MW 148.51 g/mol) for analytical method development and quality control.
The molecular framework of 1-Chloro-2-(trifluoromethoxy)ethane (C3H4ClF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H4ClF3O |
| Molecular Weight | 148.51 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-1,1,2-trifluoro-1-methoxyethane (CAS 425-87-6)
- 5-Chloro-3-nitro-1H-1,2,4-triazole (CAS 70890-47-0)
- 4-Chloro-1,2,5-oxadiazole-3-carboxylic acid (CAS 1314934-33-2)
- 5-Chloro-1,3,4-oxadiazole-2-carboxylic acid (CAS 1446409-04-6)
- 2-Chloro-5-Fluoropyrimidin-4(3H)-One (CAS 155-12-4)
- 6-Chloro-5-fluoropyrimidin-4(1H)-one (CAS 1805161-90-3)
- 2-Chloro-6-fluoropyrimidin-4-ol (CAS 1805225-46-0)
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Recommended Standards
- 2-(Chloromethoxy)-1,1,1-trifluoroethane (CAS 21937-47-3)
- 1-Chloro-1,3,3,3-tetrafluoropropene (CAS 460-71-9)
- 2,2,2-Trichloroethanamine (CAS 4088-19-1)
- 5-Fluorofuran-2-carbonyl Chloride (CAS 1173834-52-0)
- 1-(5-Bromo-2-(trifluoromethyl)pyridin-4-yl)-2,2,2-trifluoroethanone (CAS 1375303-24-4)
- 3-[(dimethylamino)methyl]furan-2-carboxylic acid hydrochloride (CAS 1803612-01-2)
- 2-[4-(propan-2-yl)phenyl]-2-{4h,5h,6h,7h-thieno[3,2-c]pyridin-5-yl}ethan-1-amine (CAS 1021233-79-3)
- 2-(1-Methyl-1h-1,3-benzodiazol-2-yl)ethanethioamide (CAS 61689-99-4)
- Veraguensin (CAS 19950-55-1)
- 5-((Methylamino)methyl)-N-phenylpyrimidin-2-amine (CAS 944450-95-7)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid (CAS 171860-40-5)
- tert-Butyl 4-(2-(4-methylpyridin-3-yl)ethyl)piperazine-1-carboxylate (CAS 2602340-72-5)
- 2-Oxa-8-azaspiro[4.5]decan-4-one (CAS 2227205-76-5)
- Des-Phe22-Tirzepatide (CAS CATO-CPTD788951)
Why CATO?
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