6-Chloro-5-fluoropyrimidin-4(1H)-one CAS 1805161-90-3
| CAS No. | 1805161-90-3 |
| Molecular Formula | C4H2ClFN2O |
| Molecular Weight | 148.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Chloro-5-fluoropyrimidin-4(1H)-one is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Chloro-5-fluoropyrimidin-4(1H)-one (CAS 1805161-90-3) is a high-purity analytical reference standard with the molecular formula C4H2ClFN2O and a molecular weight of 148.52 g/mol.
The molecular framework of 6-Chloro-5-fluoropyrimidin-4(1H)-one (C4H2ClFN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Chloro-5-fluoropyrimidin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H2ClFN2O |
| Molecular Weight | 148.52 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-5-Fluoropyrimidin-4(3H)-One (CAS 155-12-4)
- 2-Chloro-6-fluoropyrimidin-4-ol (CAS 1805225-46-0)
- 4-Chloro-6-fluoropyrimidin-5-ol (CAS 1805639-49-9)
- 2-Chloro-4-fluoropyrimidin-5-ol (CAS 1807115-17-8)
- 1-Chloro-2-(trifluoromethoxy)ethane (CAS 1645-95-0)
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- 5-Fluorofuran-2-carbonyl Chloride (CAS 1173834-52-0)
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- Ethephon D4 (2-Chloroethyl-1,1,2,2 D4) (CAS 1020719-29-2)
- 2-(2-Chloropyridin-3-yl)-1-(3,4-dichlorobenzyl)-1H-benzo[d]imidazole (CAS 338411-21-5)
- (S)-2-(2-fluorophenyl)-2-(methylamino)ethan-1-ol (CAS 1213537-80-4)
- 2-Amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one (CAS 3470-55-1)
- 5-(1,3-Dioxolan-2-yl)furan-2-carbaldehyde (CAS 117953-13-6)
- 6-Methoxy-2,3-dihydrobenzofuran-2-carboxylic acid (CAS 41910-91-2)
- 5-Bromo-2-(naphthalen-1-ylmethoxy)benzaldehyde (CAS 430450-38-7)
- N-(3-Chloro-4-fluorophenyl)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide (CAS 329058-93-7)
- 7-Chloro-2-(3-chlorophenyl)-3,8-dimethylquinoline-4-carboxylic acid (CAS 862785-61-3)
- <I>N</I>-Sulfenylanilide (CAS 1122-83-4)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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