3,3-Difluoro-1-(hydroxymethyl)cyclobutane-1-carboxylic acid CAS 1645565-01-0
| CAS No. | 1645565-01-0 |
| Molecular Formula | C6H8F2O3 |
| Molecular Weight | 166.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3,3-Difluoro-1-(hydroxymethyl)cyclobutane-1-carboxylic acid (C6H8F2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
3,3-Difluoro-1-(hydroxymethyl)cyclobutane-1-carboxylic acid (CAS 1645565-01-0), molecular formula C6H8F2O3 and molecular weight 166.12 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3,3-Difluoro-1-(hydroxymethyl)cyclobutane-1-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8F2O3 |
| Molecular Weight | 166.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related Difluoro Standards
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Recommended Standards
- 3,3-Difluorotetrahydro-2H-pyran-4-carboxylic acid (CAS 1504681-05-3)
- 5,5-difluorotetrahydropyran-2-carboxylic acid (CAS 1426135-66-1)
- 2-(difluoromethyl)furan-3-carboxylic acid (CAS 1655558-07-8)
- 3-(Difluoromethyl)-3-hydroxycyclobutane-1-carboxylic acid (CAS 1423034-50-7)
- N-((3-Fluoropyrrolidin-3-yl)methyl)ethanamine (CAS 125032-85-1)
- Benzyl 4-Aminobenzylcarbamate (CAS 168050-39-3)
- 2-Amino-N-benzylacetamide hydrochloride (CAS 20432-97-7)
- 4-iodo-1-N-methylbenzene-1,2-diamine dihydrochloride (CAS 1864073-55-1)
- 4-(3-aminoisoxazolo[5,4-b]pyridin-5-yl)-2-thiazol-2-yl-but-3-yn-2-ol (CAS 2593980-01-7)
- Omeprazole Impurity 63 (CAS 1105933-54-7)
- 2-cyclobutylacetaldehyde (CAS 6540-31-4)
- Azirino[2,3-b]indole (CAS 112623-90-2)
- [1-(aminomethyl)-2,2-dimethylcyclopropyl]methanol (CAS 1340463-43-5)
- Semaglutide impurity 275 (CAS CATO-C4X-2226275)
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