5-Chloro-1-(4-nitrobenzyl)-3-phenyl-1H-indole-2-carboxamide CAS 339098-47-4
| CAS No. | 339098-47-4 |
| Molecular Formula | C22H16ClN3O3 |
| Molecular Weight | 405.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-1-(4-nitrobenzyl)-3-phenyl-1H-indole-2-carboxamide (CAS 339098-47-4), molecular formula C22H16ClN3O3 and molecular weight 405.83 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Chloro-1-(4-nitrobenzyl)-3-phenyl-1H-indole-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 405.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-1-(4-nitrobenzyl)-3-phenyl-1H-indole-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16ClN3O3 |
| Molecular Weight | 405.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- N-(3-chloro-4-(cyano(phenyl)methyl)phenyl)-3-methyl-5-nitrobenzamide (CAS 1646643-53-9)
- 2-(7-Chloro-4-oxoquinazolin-3(4H)-yl)-N-(4-phenoxyphenyl)acetamide (CAS 618444-17-0)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-3-(3,4-dimethoxyphenyl)thiourea (CAS 326815-17-2)
- 4-{[(E)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]amino}-N,N-dimethylbenzene-1-sulfonamide (CAS 303997-75-3)
- 4-Chloro-6-phenyl-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine-5-carbonitrile (CAS 303985-09-3)
- Ethyl 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 339102-32-8)
- 3-(6-Chloro-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-8-oxa-3-azabicyclo[3.2.1]octane (CAS 1144080-35-2)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 502968-59-4)
Recommended Standards
- 3-(4-Chlorophenyl)-N-(4-methoxyphenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide (CAS 320417-61-6)
- N-(4-Chlorophenyl)-3-(4-methoxyphenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide (CAS 338975-87-4)
- 1-(5-(4-Chlorophenyl)-7-phenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)pyrrolidine-2,5-dione (CAS 489414-69-9)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 227958-10-3)
- N-(5-(Phenylsulfonamido)-1,3,4-thiadiazol-2-yl)butyramide (CAS 89782-65-0)
- 1-(4-Iodo-3-methylphenyl)ethan-1-one (CAS 52107-80-9)
- 5-(Difluoromethyl)-6-(trifluoromethyl)pyridine-2,4-diamine (CAS 1803670-51-0)
- 3-(7-Methoxy-2-oxo-2H-chromen-3-yl)propanoic acid (CAS 1365940-08-4)
- (2Z,2'Z)-4,4'-(1,3-Phenylenebis(azanediyl))bis(4-oxobut-2-enoic acid) (CAS 13161-99-4)
- Carvedilol-D4 (CAS CATO-C4X-157431)
- (1-(4-Chloro-5-methylpyrimidin-2-yl)piperidin-4-yl)methanol (CAS 1261235-17-9)
- 2-Amino-6-methylpyridin-3-ol (CAS 20348-16-7)
- 1-Ethyl-3-phenylpiperazine-2,5-dione (CAS 1214164-70-1)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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