3-Iodo-2-methylthiophene CAS 16494-34-1
| CAS No. | 16494-34-1 |
| Molecular Formula | C5H5IS |
| Molecular Weight | 224.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Iodo-2-methylthiophene is closely related to sulfur-containing functionality, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Iodo-2-methylthiophene (CAS 16494-34-1) is a high-purity analytical reference standard with the molecular formula C5H5IS and a molecular weight of 224.06 g/mol.
Owing to sulfur-containing functionality, iodine substitution, 3-Iodo-2-methylthiophene is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 224.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5IS |
| Molecular Weight | 224.06 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | I-containing |
| Sulfur Atoms | 1 |
Related Iodo Standards
- 2-Iodo-4-methylthiophene (CAS 16488-58-7)
- 2-Iodo-3-methylthiophene (CAS 16494-40-9)
- 3-Iodo-4-methylthiophene (CAS 16494-41-0)
- 6-Iodo-2-oxaspiro[3.3]heptane (CAS 1363381-15-0)
- 1-iodo-3-methoxybicyclo[1.1.1]pentane (CAS 136863-37-1)
- 1-Iodo-3-methylcyclohexane (CAS 89894-77-9)
- 1-iodo-4-methylcyclohexane (CAS 65500-78-9)
- 1-iodo-2-trimethylsilylacetylene (CAS 18163-47-8)
Recommended Standards
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