4,6-Difluoro-N-methylpyrimidin-2-amine CAS 165258-57-1
| CAS No. | 165258-57-1 |
| Molecular Formula | C5H5F2N3 |
| Molecular Weight | 145.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,6-Difluoro-N-methylpyrimidin-2-amine.
CATO supplies 4,6-Difluoro-N-methylpyrimidin-2-amine (CAS 165258-57-1), a certified reference material (molecular formula C5H5F2N3, MW 145.11 g/mol) for analytical method development and quality control.
Based on its molecular formula C5H5F2N3, 4,6-Difluoro-N-methylpyrimidin-2-amine contains a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 145.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,6-Difluoro-N-methylpyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H5F2N3 |
| Molecular Weight | 145.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoro Standards
- (2,6-Difluoro-3-pyridyl)methanol (CAS 1105510-11-9)
- 3,5-Difluoro-2-methoxypyridine (CAS 1171918-06-1)
- 2,6-Difluoro-4-methoxypyridine (CAS 1184172-35-7)
- 3,5-Difluoro-4-methoxypyridine (CAS 1186195-24-3)
- 2,5-Difluoro-4-methoxypyridine (CAS 1210868-65-7)
- 3,6-Difluoro-2-methoxypyridine (CAS 1214323-06-4)
- 2,6-Difluoro-3-methoxypyridine (CAS 1214331-52-8)
- 2,3-Difluoro-6-methoxypyridine (CAS 1227564-48-8)
Recommended Standards
- 2-Amino-4,5-difluorophenol (CAS 163734-01-8)
- 2,6-Difluoro-N-methylpyrimidin-4-amine (CAS 165258-58-2)
- 4-Amino-2,3-difluorophenol (CAS 163733-99-1)
- 6-(Difluoromethyl)pyrimidin-4-amine (CAS 1706464-15-4)
- Methyl 2-(1H-pyrrol-1-yl)propanoate (CAS 130016-69-2)
- Methyl 3-(((2,3-dihydro-1h-inden-5-yl)oxy)methyl)benzoate (CAS 832739-22-7)
- Mirabegron Impurity 77 (CAS 6397-70-2)
- Methyl 4-[3-(benzyloxy)phenyl]-3-fluorobenzoate (CAS 1820711-73-6)
- n-Benzyl-2-hydroxy-5-iodobenzamide (CAS 13156-80-4)
- rel-(2S)-3-[(4R)-4-ethyl-2,5-dioxo-imidazolidin-4-yl]-2-methyl-propanoic acid (CAS 1957283-60-1)
- 4-Chloro-N-(4-chlorophenyl)-N-(1,1-dioxido-2,3-dihydrothiophen-3-yl)benzamide (CAS 303094-05-5)
- 2-(Aminomethyl)-5-chloro-3-(difluoromethyl)pyridine-4-carboxaldehyde (CAS 1805369-83-8)
- 1-(tert-Butyl) 24-(2,5-dioxopyrrolidin-1-yl) 4,20-dioxo-7,10,13,16-tetraoxa-2,3,19-triazatetracosanedioate (CAS 1203507-50-9)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com