Evocalcet impurity 52 CAS 1666124-30-6
| CAS No. | 1666124-30-6 |
| Molecular Formula | C26H30N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 439.00 g/mol gives Evocalcet impurity 52 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Evocalcet impurity 52 (CAS 1666124-30-6), a pharmacopoeial impurity reference standard (molecular formula C26H30N2O2HCl, MW 439.00 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Evocalcet impurity 52 (C26H30N2O2HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Evocalcet impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H30N2O2 HCl |
| Molecular Weight | 439.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Evocalcet Standards
- Evocalcet Impurity 27 (CAS 1039631-63-4)
- Evocalcet Impurity 30 (CAS 1039631-66-7)
- Evocalcet Impurity 29 (CAS 1092366-92-1)
- Evocalcet Impurity 73 (CAS 15297-34-4)
- Evocalcet Impurity 33 HCl (CAS 1666124-29-3)
- Evocalcet Impurity 4 HCl (CAS 1666124-30-6 (free base))
- Evocalcet Impurity 17 (CAS 210367-24-1)
- Evocalcet impurity 53 (CAS 2107154-97-0)
Recommended Standards
- Rifamycin impurity 20 (CAS 32259-67-9)
- Cefminox impurity 51 (CAS CATO-C4X-192651)
- Midazolam Impurity 18 (CAS CATO-C4X-150918)
- 2-Methyl-4-sulfamoylbenzoic acid (CAS 860752-46-1)
- 2-Chloro-4-(difluoromethoxy)benzenethiol (CAS 1807213-34-8)
- 7,7-Dimethoxy-1-(phenylthio)octahydroindolizine (CAS 62240-38-4)
- 2-Amino-6-fluoro-3-nitrobenzoic acid (CAS 910123-26-1)
- Methyl 3-(2-(3-acetylphenoxy)ethoxy)benzoate (CAS 937601-96-2)
- (2,4-Dichloropyrimidin-5-yl)methanamine (CAS 933685-97-3)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
Why CATO?
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