Conjugated Estrogens EP Impurity H CAS 16680-48-1
| CAS No. | 16680-48-1 |
| Molecular Formula | C18H17NaO5S |
| Molecular Weight | 368.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Conjugated Estrogens EP Impurity H is closely related to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Conjugated Estrogens EP Impurity H (CAS 16680-48-1) is a certified pharmaceutical impurity reference standard with the molecular formula C18H17NaO5S and a molecular weight of 368.38 g/mol.
Conjugated Estrogens EP Impurity H (C18H17NaO5S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Conjugated Estrogens EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17NaO5S |
| Molecular Weight | 368.38 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Sulfur Atoms | 1 |
Related Conjugated Standards
- Conjugated Estrogens EP Impurity E (CAS 56086-66-9)
- Conjugated Estrogens EP Impurity F (CAS 16680-50-5)
- Conjugated Estrogens EP Impurity G(Stabilzed with up to 40% Tromethamine) (CAS 61612-83-7)
- Conjugated Estrogens EP Impurity C (CAS 16680-49-2)
- Conjugated Estrogens EP Impurity A (CAS 56050-04-5)
- Conjugated Estrogens Impurity 17 (CAS CATO-C4X-141617)
- Conjugated Linoleic Acid Ethyl Ester, 90% (Mixture of Isomers) (CAS 137142-61-1)
- Conjugated Linoleic Acid Methyl Ester (CAS 1002-79-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com