Conjugated Estrogens EP Impurity G(Stabilzed with up to 40% Tromethamine) CAS 61612-83-7
| CAS No. | 61612-83-7 |
| Molecular Formula | C18H19NaO5S |
| Molecular Weight | 370.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Conjugated Estrogens EP Impurity G(Stabilzed with up to 40% Tromethamine) (CAS 61612-83-7) is a certified pharmaceutical impurity reference standard with the molecular formula C18H19NaO5S and a molecular weight of 370.40 g/mol.
The molecular framework of Conjugated Estrogens EP Impurity G(Stabilzed with up to 40% Tromethamine) (C18H19NaO5S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19NaO5S |
| Molecular Weight | 370.40 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Sulfur Atoms | 1 |
Related Conjugated Standards
- Conjugated Estrogens EP Impurity E (CAS 56086-66-9)
- Conjugated Estrogens EP Impurity F (CAS 16680-50-5)
- Conjugated Estrogens EP Impurity C (CAS 16680-49-2)
- Conjugated Estrogens EP Impurity H (CAS 16680-48-1)
- Conjugated Estrogens EP Impurity A (CAS 56050-04-5)
- Conjugated Estrogens Impurity 17 (CAS CATO-C4X-141617)
- Conjugated Linoleic Acid Ethyl Ester, 90% (Mixture of Isomers) (CAS 137142-61-1)
- Conjugated Linoleic Acid Methyl Ester (CAS 1002-79-5)
Recommended Standards
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