Fasudil Impurity 10 CAS 166895-76-7
| CAS No. | 166895-76-7 |
| Molecular Formula | C14H17N3O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Fasudil Impurity 10 (C14H17N3O2SHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Fasudil Impurity 10 (CAS 166895-76-7) is a certified pharmaceutical impurity reference standard with the molecular formula C14H17N3O2SHCl and a molecular weight of 327.83 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fasudil Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17N3O2S HCl |
| Molecular Weight | 327.83 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fasudil Standards
- Fasudil Impurity 49 (CAS 103745-39-7)
- Fasudil Impurity 17 (CAS 105627-79-0)
- Fasudil Impurity 38 (CAS 105627-80-3)
- Fasudil Hydrochloride (CAS 105628-07-7)
- Fasudil Impurity 47 (CAS 105628-70-4)
- Fasudil Hydroxy (CAS 105628-72-6)
- Fasudil Impurity 23 DiHCl (CAS 116700-36-8)
- Fasudil Impurity 32 (CAS 116970-50-4)
Recommended Standards
- Itraconazole Impurity 21 (CAS CATO-C4X-149721)
- Moxifloxacin Impurity 45 (CAS 112811-65-1)
- Atovaquone EP Impurity C (CAS 1809464-27-4)
- Methyl (2S,4S)-4-[2-(methoxycarbonyl)phenoxy]-2-pyrrolidinecarboxylate hydrochloride (CAS 1354486-85-3)
- N-(9-Ethyl-9H-carbazol-3-yl)-2-(4-methyl-2,5-dioxo-4-(p-tolyl)imidazolidin-1-yl)acetamide (CAS 956357-71-4)
- Cis-5-Dodecenoic Acid (CAS 2430-94-6)
- N-(3,4-dichlorophenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 868256-47-7)
- 3-{[(4-methylphenyl)methyl]sulfanyl}-1h-1,2,4-triazole (CAS 302804-66-6)
- 3-(Cyclopropylmethoxy)-N,N-diethyl-4-iodobenzamide (CAS 1309682-65-2)
- Acetyl Dipeptide-1 (CAS 196604-48-5)
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