Atovaquone EP Impurity C CAS 1809464-27-4
| CAS No. | 1809464-27-4 |
| Molecular Formula | C22H17ClO3 |
| Molecular Weight | 364.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Atovaquone EP Impurity C (CAS 1809464-27-4), a pharmacopoeial impurity reference standard (molecular formula C22H17ClO3, MW 364.82 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Atovaquone EP Impurity C (C22H17ClO3) contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 364.82 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Atovaquone EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H17ClO3 |
| Molecular Weight | 364.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
Related Atovaquone Standards
- Atovaquone EP Impurity B (RC A) (CAS 137732-39-9)
- Atovaquone (CAS 95233-18-4)
- Atovaquone EP Impurity A (CAS 2517583-91-2)
- cis-Atovaquone-d5 (contains 10% trans isomer) (CAS 1217612-80-0)
- Atovaquone-d5 (CAS 1329792-63-3)
- Atovaquone Impurity 9 (CAS 1100053-58-4)
- Atovaquone EP Impurity D (CAS 129700-41-0)
- Atovaquone Impurity 1 (CAS 49708-81-8)
Recommended Standards
- 4-Chloroquinazoline-6,7-diyl bis(2,2-dimethylpropanoate) (CAS 1145671-34-6)
- 2,2-Dibromo-1-(2,6-dichloro-3-fluorophenyl)ethanone (CAS 1820604-17-8)
- 2-(2-(2-Chloro-7,8-dimethylquinolin-3-yl)ethyl)isoindoline-1,3-dione (CAS 1105194-11-3)
- 1-((2-Chlorobenzyl)oxy)-2-(4-methoxyphenyl)-1H-benzo[d]imidazole (CAS 339009-73-3)
- Ruxolitinib Impurity 29 (CAS CATO-C4X-205829)
- Parecoxib sodium Impurity 10 (CAS 2229657-81-0)
- Lisinopril Impurity 16 (CAS CATO-C4X-168116)
- 5-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-4-ethyl-4H-1,2,4-triazole-3-thiol (CAS 344268-56-0)
- Indole-3-carbinol (CAS 700-06-1)
- Topiramate Impurity 28 (CAS 53209-16-8)
- 5-(4-Methylphenyl)pyridine-3-carboxylic Acid (CAS 893737-23-0)
- 7028-70-8 Ethyl 4-[4-(methylsulfanyl)phenyl]-4-oxobutanoate DTXSID20645598 (CAS 7028-70-8)
- 1-(4-Chloro-3-ethylphenyl)ethanone (CAS 860537-23-1)
- Crustacean Cardioactive Peptide (CAS 107090-96-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com