| CAS No. | 166964-40-5 |
| Molecular Formula | C8H8Cl2O2S |
| Molecular Weight | 239.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 239.12 g/mol gives 3-Chloro-2,5-dimethylbenzenesulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Chloro-2,5-dimethylbenzenesulfonyl chloride (CAS 166964-40-5), a certified reference material (molecular formula C8H8Cl2O2S, MW 239.12 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloro-2,5-dimethylbenzenesulfonyl chloride (C8H8Cl2O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Chloro-2,5-dimethylbenzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C8H8Cl2O2S |
| Molecular Weight | 239.12 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |