6-Fluoro-5-iodonicotinic acid CAS 1674401-96-7
| CAS No. | 1674401-96-7 |
| Molecular Formula | C6H3FINO2 |
| Molecular Weight | 267.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Fluoro-5-iodonicotinic acid (CAS 1674401-96-7), molecular formula C6H3FINO2 and molecular weight 267.00 g/mol, is a CATO reference standard with documented purity and traceability.
6-Fluoro-5-iodonicotinic acid (C6H3FINO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3FINO2 |
| Molecular Weight | 267.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 1-Fluoro-2-iodo-3-nitrobenzene (CAS 122455-36-1)
- 2-Fluoro-1-iodo-3-nitrobenzene (CAS 1261782-23-3)
- 2-Fluoro-5-iodonicotinic acid (CAS 1334721-89-9)
- 4-Fluoro-6-iodopicolinic acid (CAS 1393531-73-1)
- 6-Fluoro-4-iodopicolinic acid (CAS 1393569-15-7)
- 3-Fluoro-2-iodopyridine-4-carboxylic acid (CAS 153035-09-7)
- 1-Fluoro-2-iodo-4-nitrobenzene (CAS 177363-10-9)
- 3-Fluoro-4-iodopicolinic acid (CAS 1803766-95-1)
Recommended Standards
- 2-Fluoro-3-iodoisonicotinic acid (CAS 1803819-34-2)
- 2-Fluoro-5-iodoisonicotinic acid (CAS 1804496-73-8)
- 6-Fluoro-4-iodonicotinic acid (CAS 1805064-67-8)
- 6-Bromo-2-(trifluoromethyl)oxazolo[4,5-b]pyridine (CAS 1260656-87-8)
- 1-Boc-N-(4-pyridylmethyl)piperidin-4-amine (CAS 206274-24-0)
- 5-(4-Methylpent-3-en-1-yl)-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione (CAS 29811-04-9)
- (S)-1-((S)-2-Acetamidopropanoyl)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide (CAS 60240-13-3)
- 5-Bromo-4-fluoro-N1-methylbenzene-1,2-diamine (CAS 1600342-90-2)
- Fosaprepitant impurity 54（R,S,S） (CAS CATO-C4X-116854)
- 2-((4-Nitrobenzyl)oxy)benzaldehyde (CAS 17490-72-1)
- 2-Amino-3,5-difluorobenzyl Alcohol (CAS 1378824-82-8)
- 2-(1-Methyl-1H-pyrrol-2-yl)-2-oxo-N-[2-(trifluoromethyl)phenyl]acetamide (CAS 477871-99-1)
- Benzyl ethyl((1-(2-hydroxyethyl)piperidin-2-yl)methyl)carbamate (CAS 1353972-86-7)
- C-Peptide 2 (rat) (CAS 41594-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com