Fosaprepitant impurity 54（R,S,S） CAS CATO-C4X-116854
| CAS No. | CATO-C4X-116854 |
| Molecular Formula | C23H22F7N4O6P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fosaprepitant impurity 54（R,S,S） (C23H22F7N4O6PC7H17NO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Fosaprepitant impurity 54（R,S,S） (CAS CATO-C4X-116854, C23H22F7N4O6PC7H17NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fosaprepitant impurity 54（R,S,S） under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H22F7N4O6P 2*C7H17NO5 |
| Molecular Weight | 809.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fosaprepitant Standards
- Fosaprepitant impurity 55（R,S,R） (CAS 1185503-00-7(free base))
- Fosaprepitant Impurity 53 (CAS 1254261-32-9)
- Fosaprepitant Impurity 4 Dimeglumine (CAS 1523569-87-0)
- Fosaprepitant Impurity 19 (CAS 1623-07-0)
- Fosaprepitant Impurity 48 (CAS 1707-92-2)
- Fosaprepitant Impurity 6 (CAS 172822-01-4（free base）)
- Fosaprepitant Impurity 12 (CAS 2035475-10-4)
- Fosaprepitant Impurity 41 HCl (CAS 2377328-02-2)
Recommended Standards
- Dotinurad Impurity 169 (CAS CATO-C4X-2494169)
- Budesonide Impurity 71 (CAS 91160-87-1)
- Cefcapene Impurity 18 (CAS CATO-C4X-182418)
- Ertugliflozin impurity 28 (CAS CATO-C4X-301128)
- ((Tert-butyldimethylsilyl)imino)(fluoromethyl)(phenyl)-λ6-sulfanone (CAS 825638-25-3)
- (S)-2-(((Benzyloxy)carbonyl)amino)-4-(cyclohexyloxy)-4-oxobutanoic acid (CAS 211797-21-6)
- 2-Amino-5-bromo-3-fluorobenzamide (CAS 1295570-35-2)
- (E)-2-(2-((2,6-dimethylphenyl)amino)vinyl)-4-(4-heptylphenyl)-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile (CAS 685107-72-6)
- Tetraethyl ethene-1,1-diylbis(phosphonate) (CAS 37465-31-9)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com