Nicardipine Impurity 19 CAS 167963-66-8
| CAS No. | 167963-66-8 |
| Molecular Formula | C18H17N3O6 |
| Molecular Weight | 371.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nicardipine Impurity 19 (CAS 167963-66-8), a pharmacopoeial impurity reference standard (molecular formula C18H17N3O6, MW 371.34 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Nicardipine Impurity 19 (C18H17N3O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H17N3O6 |
| Molecular Weight | 371.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2004 |
| Nitrogen Atoms | 3 |
Related Nicardipine Standards
- Nicardipine Impurity 35 (CAS CATO-C4X-171035)
- Nicardipine Impurity 17 (CAS 85677-95-8)
- Nicardipine Impurity 62 (CAS CATO-C4X-171062)
- Nicardipine Impurity 23 (CAS 87966-39-0)
- Nicardipine Impurity 37 (CAS CATO-C4X-171037)
- Nicardipine Impurity 42 (CAS CATO-C4X-171042)
- Nicardipine Impurity 48 (CAS CATO-C4X-171048)
- Nicardipine Impurity 31 (CAS CATO-C4X-171031)
Recommended Standards
- Methyl 2-benzamido-3-(((4-nitrobenzyl)oxy)imino)propanoate (CAS 318284-55-8)
- 4,9-Diphenylnaphtho[2,3-c]furan-1,3-dione (CAS 5342-35-8)
- Nedocromil (CAS 69049-73-6)
- (S)-1-(3,5-Bis(trifluoromethyl)phenyl)-3-(pyrrolidin-2-ylmethyl)thiourea (CAS 904928-30-9)
- Ibrutinib Impurity 64 (CAS CATO-C4X-106464)
- Venlafaxine Impurity 34 (CAS 93413-76-4)
- Balsalazide Impurity 5 (CAS 1346606-53-8)
- Dotinurad Impurity 165 (CAS CATO-C4X-2494165)
- 2-(1-Methyl-1h-imidazol-5-yl)tetrahydro-2h-pyran-4-amine (CAS 1489592-90-6)
- 6-Cyclopropylisoquinolin-1(2H)-one (CAS 1472041-31-8)
- (3-Chloro-5-fluorophenyl)(phenyl)methanol (CAS 842140-65-2)
- Ethyl 7-bromobenzo[d]thiazole-2-carboxylate (CAS 1188170-07-1)
- 4-methoxy-3-(2-methoxyethoxy)aniline (CAS 26181-51-1)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com