Dotinurad Impurity 165 CAS CATO-C4X-2494165
| CAS No. | CATO-C4X-2494165 |
| Molecular Formula | C22H20Cl2N2O2S2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Dotinurad Impurity 165 (CAS CATO-C4X-2494165, C22H20Cl2N2O2S2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Dotinurad Impurity 165 (C22H20Cl2N2O2S2HCl) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Dotinurad Impurity 165 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H20Cl2N2O2S2 HCl |
| Molecular Weight | 515.89 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Dotinurad Standards
- Dotinurad Impurity 118 (CAS 127817-86-1)
- Dotinurad (CAS 1285572-51-1)
- Dotinurad Impurity 11 (CAS 1285572-54-4)
- Dotinurad Impurity 3 (CAS 1285572-55-5)
- Dotinurad Impurity 7 (CAS 1285572-63-5)
- Dotinurad Impurity 109 (CAS 1285572-82-8)
- Dotinurad Impurity 136 (CAS 1285572-83-9)
- Dotinurad Impurity 5 (CAS 1285572-89-5)
Recommended Standards
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- Lasmiditan Impurity 42 (CAS CATO-C4X-247842)
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- Methyl 6-bromoimidazo[1,2-a]pyridine-8-carboxylate hydrochloride (CAS 1332581-63-1)
- Ampicillin Impurity 46 (CAS CATO-C4X-144346)
- 4-Bromo-3-chloro-2-(difluoromethyl)pyridine-6-acetic acid (CAS 1805341-30-3)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com