Brimonidine EP Impurity E CAS 168329-48-4
| CAS No. | 168329-48-4 |
| Molecular Formula | C9H8BrN5 |
| Molecular Weight | 266.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Brimonidine EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Brimonidine EP Impurity E (CAS 168329-48-4), a pharmacopoeial impurity reference standard (molecular formula C9H8BrN5, MW 266.10 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Brimonidine EP Impurity E (C9H8BrN5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 266.10 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C9H8BrN5 |
| Molecular Weight | 266.10 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
Related Brimonidine Standards
- Brimonidine Impurity 22 (CAS 134892-46-9)
- Brimonidine Impurity 42 (CAS CATO-C4X-156642)
- Brimonidine Related Impurity 4 (CAS 182628-02-0)
- Brimonidine EP Impurity D (CAS 842138-74-3)
- Brimonidine Impurity 20 (CAS 1217439-05-8)
- Brimonidine Impurity 15 (CAS 91147-46-5)
- Brimonidine Impurity 24 (CAS CATO-C4X-156624)
- Brimonidine Impurity 25 (CAS 135306-57-9)
Recommended Standards
- tert-Butyl 2,6-dichloro-5-fluoronicotinate (CAS 932705-76-5)
- N-(4-Bromo-2-hydroxyphenyl)methanesulfonamide (CAS 105295-63-4)
- n2-(4-Bromophenyl)-1,3,5-triazine-2,4-diamine (CAS 72274-25-0)
- 5-(4-Bromo-2-fluorophenyl)-2-methylpyridine (CAS 1187163-44-5)
- Dasatinib Impurity 34 (CAS CATO-C4X-160734)
- Dl-Lysine Acetylsalicylate EP Impurity J (CAS CATO-C4X-22115)
- Ertapenem Impurity 31 (CAS CATO-C4X-163331)
- 4-((6-Methoxyquinolin-4-yl)oxy)aniline (CAS 1220892-82-9)
- Pyrrolidin-3-ylmethanesulfonamide (CAS 95596-30-8)
- 4-Amino-5-(methoxycarbonyl)isothiazole-3-carboxylic acid (CAS 2055841-46-6)
- Fexofenadine EP Impurity D (CAS 154825-96-4)
- 4-Fluoro-3-iodobenzonitrile (CAS 159719-57-0)
- 1-Benzyl-1H-pyrazolo[4,3-c]pyridine (CAS 41373-11-9)
- Liraglutide Impurity 6 TFA Salt (CAS CATO-C4X-19926)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com