Ethyl 2,2-difluoro-3-hydroxy-3-methylbutanoate CAS 168558-19-8
| CAS No. | 168558-19-8 |
| Molecular Formula | C7H12F2O3 |
| Molecular Weight | 182.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Ethyl 2,2-difluoro-3-hydroxy-3-methylbutanoate (C7H12F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 182.17 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Ethyl 2,2-difluoro-3-hydroxy-3-methylbutanoate (CAS 168558-19-8), molecular formula C7H12F2O3 and molecular weight 182.17 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 2,2-difluoro-3-hydroxy-3-methylbutanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H12F2O3 |
| Molecular Weight | 182.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
Related Ethyl Standards
- Ethyl 2,2-difluoro-3-hydroxypentanoate (CAS 1092693-68-9)
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Recommended Standards
- Methyl 2-(2,3-dihydroxyphenyl)acetate (CAS 168481-87-6)
- 3-Ethyl-2,2-difluoro-3-hydroxypentanoic acid (CAS 168558-23-4)
- Methyl 2,6-dihydroxy-4-methylbenzoate (CAS 16846-10-9)
- 4-(2-Hydroxyethoxy)benzoic acid (CAS 1711-24-6)
- 6-Bromo-2-chloro-5-methylpyrido[2,3-d]pyrimidin-7-amine (CAS 1908455-60-6)
- 3-(5-(Aminomethyl)-4H-1,2,4-triazol-3-yl)benzonitrile (CAS 944897-08-9)
- Sodium 1-hydroxy-3-(quinolin-6-yl)propane-1-sulfonate (CAS 1609934-65-7)
- tert-Butyl 3-(3-fluorophenyl)piperazine-1-carboxylate (CAS 886767-17-5)
- 2-(4-(Benzyloxy)-2-chlorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane (CAS 2096997-57-6)
- (E,Z)-2,6-dodecadien-1-al (CAS 21662-13-5)
- Methyl 4-(2,4-dimethoxyphenyl)-2-fluorobenzoate (CAS 1820648-16-5)
- Methyl 2-(propa-1,2-dien-1-yl)benzoate (CAS 159527-73-8)
- 35383-65-4 7-Oxodecanoic acid MFCD01320170 (CAS 35383-65-4)
- semaglutide (CAS 782487-28-9)
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