Linezolid Impurity 54 CAS 168828-65-7
| CAS No. | 168828-65-7 |
| Molecular Formula | C15H18FN3O4 |
| Molecular Weight | 323.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Linezolid Impurity 54 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Linezolid Impurity 54 (CAS 168828-65-7), a pharmacopoeial impurity reference standard (molecular formula C15H18FN3O4, MW 323.32 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Linezolid Impurity 54 (C15H18FN3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H18FN3O4 |
| Molecular Weight | 323.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Linezolid Standards
- Linezolid USP Related Compound A (CAS 168828-84-0)
- Linezolid Impurity 99 (CAS CATO-C4X-107399)
- Linezolid Impurity 117 (CAS 352665-38-4)
- Linezolid Impurity 8 (CAS 556801-15-1)
- Linezolid Impurity 45 (CAS 168828-81-7)
- Linezolid Impurity 82 (CAS CATO-C4X-107382)
- Linezolid Impurity 29 (CAS 496031-57-3)
- Linezolid impurity 106 (CAS 1644566-15-3)
Recommended Standards
- Tolcapone 5-amino-3-O-sulfate (CAS 254902-29-9)
- Iguratimod Impurity 50 (CAS CATO-C4X-182650)
- N-((1-(4-Fluorophenyl)-1H-tetrazol-5-yl)methyl)-3-phenylacrylamide (CAS 897623-57-3)
- N-(Benzo[c][1,2,5]thiadiazol-4-yl)-6-(1H-imidazol-1-yl)pyridazine-3-carboxamide (CAS 1396875-38-9)
- Entecavir EP Impurity C (CAS 2204369-23-1)
- Pirfenidone Impurity 39 (CAS 51566-22-4)
- Rasagiline Impurity 14 HCl (CAS 200628-33-7)
- 1001346-35-5 N~3~-(2-Methoxyethyl)-N-methyl-beta-alaninamide DTXSID10651269 (CAS 1001346-35-5)
- 3-(oxan-2-yl)piperidine hydrochloride (CAS 1955493-52-3)
- Methyl (s)-3-amino-3-mesitylpropanoate (CAS 1213367-43-1)
- (S)-4-Chloro-2-(4-methoxybut-1-yn-1-yl)-3-methyl-1-(piperidin-3-yl)-1H-pyrrolo[2,3-b]pyridine-6-carboxamide (CAS 1681021-52-2)
- 1-[2-chloro-5-(trifluoromethyl)phenyl]-5-pyridin-4-yl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1351779-28-6)
- methyl 1-cyclopentylpiperidine-2-carboxylate (CAS 1543455-71-5)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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