Linezolid Impurity 45 CAS 168828-81-7
| CAS No. | 168828-81-7 |
| Molecular Formula | C18H19FN2O3 |
| Molecular Weight | 330.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 330.35 g/mol gives Linezolid Impurity 45 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Linezolid Impurity 45 (CAS 168828-81-7), a pharmacopoeial impurity reference standard (molecular formula C18H19FN2O3, MW 330.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C18H19FN2O3, Linezolid Impurity 45 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 330.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19FN2O3 |
| Molecular Weight | 330.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Linezolid Standards
- Linezolid Impurity 82 (CAS CATO-C4X-107382)
- Linezolid impurity 106 (CAS 1644566-15-3)
- Linezolid R-Isomer (CAS 872992-20-6)
- Linezolid (CAS 165800-03-3)
- Linezolid Impurity 54 (CAS 168828-65-7)
- Linezolid Impurity 4 (CAS 496031-56-2)
- Linezolid Ipurity 84 (CAS CATO-C4X-107384)
- Linezolid USP Related Compound A (CAS 168828-84-0)
Recommended Standards
- tert-Butyl 3-[4-(trifluoromethyl)phenyl]piperazine-1-carboxylate (CAS 886767-93-7)
- Tert-butyl 3-(3-(trifluoromethyl)phenyl)piperazine-1-carboxylate (CAS 886767-85-7)
- Flurbiprofen impurity 103 (CAS CATO-C4X-1444103)
- tert-Butyl 3-(2-(trifluoromethyl)phenyl)piperazine-1-carboxylate (CAS 886767-77-7)
- Docetaxel Impurity 90 (CAS CATO-C4X-161990)
- Drotaverin Impurity 77 (CAS CATO-C4X-243577)
- Cefoperazone Impurity 67 (CAS CATO-C4X-114967)
- 2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethanamine (CAS 40255-48-9)
- 6-Bromo-2-thioxo-3-(p-tolyl)-2,3-dihydroquinazolin-4(1H)-one (CAS 18009-10-4)
- 1-(2-Amino-4,6-difluorophenyl)ethanone (CAS 1632285-92-7)
- Metaraminol Impurity (CAS 52618-26-5)
- 6-amino-7-chloro-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one (CAS 337463-98-6)
- 1-(2-Methoxyphenyl)-3-(3,4,5-trifluorophenyl)propan-1-one (CAS 898777-64-5)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com