Rupatadine Impurity 36 CAS 169253-15-0
| CAS No. | 169253-15-0 |
| Molecular Formula | C19H19ClN2 |
| Molecular Weight | 310.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rupatadine Impurity 36 (CAS 169253-15-0) is a certified pharmaceutical impurity reference standard with the molecular formula C19H19ClN2 and a molecular weight of 310.82 g/mol.
Rupatadine Impurity 36 (C19H19ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rupatadine Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H19ClN2 |
| Molecular Weight | 310.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Rupatadine Standards
- Rupatadine Impurity 5 (CAS 35991-75-4)
- Rupatadine impurity 11 (CAS CATO-C4X-102711)
- Rupatadine impurity 47 (CAS CATO-C4X-102747)
- Rupatadine impurity 12 (CAS CATO-C4X-102712)
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- Rupatadine Impurity 34 (CAS 2724877-90-9)
- Rupatadine (CAS 158876-82-5)
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Recommended Standards
- 8-(4-Chlorophenoxy)-2-methylene-octanoic Acid Ethyl Ester 82258-37-5 Ethyl 8-(4-Chlorophenoxy)-2-methylen-octanoate (CAS 82258-37-5)
- Loratadine EP Impurity D (CAS 100643-71-8)
- Tert-butyl 4-amino-4-(4-chlorophenyl)piperidine-1-carboxylate (CAS 917925-59-8)
- Desloratadine EP Impurity B (CAS 183198-49-4)
- Dotinurad Impurity 157 (CAS CATO-C4X-2494157)
- Omeprazole Impurity 11 (CAS CATO-C4X-125511)
- Daraxonrasib Impurity 5 (CAS CATO-C4X-35185)
- 4-Ethoxy-6,7-dimethoxyquinoline-2-carboxylic acid (CAS 1325306-11-3)
- 1-Boc-4-methylpiperidine-4-carboxamide (CAS 343788-67-0)
- Fluoxetine impurity 48 (CAS 1429850-43-0)
- (3Z)-3-[(4-Methylphenyl)imino]-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 303984-52-3)
- 2-Cyanoethyl ether (CAS 1656-48-0)
- 2-((3,5-Difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one (CAS 501437-28-1)
- Angiotensin II Antipeptide (CAS 121379-63-3)
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