Rupatadine Impurity 34 CAS 2724877-90-9
| CAS No. | 2724877-90-9 |
| Molecular Formula | C26H26ClN3 |
| Molecular Weight | 415.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Rupatadine Impurity 34 (CAS 2724877-90-9, C26H26ClN3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Rupatadine Impurity 34 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 415.96 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H26ClN3 |
| Molecular Weight | 415.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Rupatadine Standards
- Rupatadine impurity 12 (CAS CATO-C4X-102712)
- Rupatadine Impurity 26 (CAS CATO-C4X-102726)
- Rupatadine (CAS 158876-82-5)
- Rupatadine impurity 47 (CAS CATO-C4X-102747)
- Rupatadine Impurity 38 (CAS CATO-C4X-102738)
- Rupatadine impurity 6 (CAS 156523-04-5)
- Rupatadine impurity 11 (CAS CATO-C4X-102711)
- Rupatadine Impurity 42 (CAS CATO-C4X-102742)
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- 4,5-Dimethyl-2-phenyl-1H-imidazol-1-yl acetate (CAS 802026-86-4)
- 2,2,3,3-Tetrafluoropropyl (2,2,3,3,4,4,5,5,6,6,6-undecafluorohexyl) carbonate (CAS 1980040-07-0)
- 2-Methyl-4,5,6,7-tetrahydro-2h-indazole-3-carboxylic acid (CAS 32287-00-6)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
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