Bucladesine Impurity 6 CAS 16955-44-5
| CAS No. | 16955-44-5 |
| Molecular Formula | C10H14N5O7P |
| Molecular Weight | 347.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bucladesine Impurity 6 (CAS 16955-44-5) is a certified pharmaceutical impurity reference standard with the molecular formula C10H14N5O7P and a molecular weight of 347.22 g/mol.
Bucladesine Impurity 6 (C10H14N5O7P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14N5O7P |
| Molecular Weight | 347.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 5 |
Related Bucladesine Standards
- Bucladesine Impurity 11 (CAS 21138-49-8)
- Bucladesine Impurity 10 (CAS CATO-C4X-202610)
- Bucladesine Impurity 3 (CAS 60-92-4)
- Bucladesine Impurity 9 (CAS CATO-C4X-20269)
- Bucladesine Impurity 7 (CAS CATO-C4X-20267)
- Bucladesine Calcium Salt (CAS 938448-87-4)
- Bucladesine Sodium Salt (CAS 16980-89-5)
- Bucladesine Impurity 1 (CAS 55443-13-5)
Recommended Standards
- Vidarabine Impurity 10 (CAS 26524-56-1)
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- S-Adenosyl-L-Methionine Impurity 11 (CAS 81012-86-4)
- Goserelin EP Impurity C Acetate (CAS CATO-C4X-19203)
- Eltrombopag Impurity 19 (CAS CATO-C4X-119819)
- Kitasamycin impurity 1 (CAS CATO-C4X-33801)
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- (1R)-(-)-10-Camphorsulfonamide (CAS 72597-34-3)
- 2-Methyl-1-(3-methylthiophen-2-yl)propan-2-ol (CAS 1314972-47-8)
- 2-(6-Amino-2-(difluoromethyl)-5-methoxypyridin-3-yl)acetic acid (CAS 1805011-75-9)
- Liraglutide(10-22)TFA Salt (CAS CATO-C4X-199211)
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