2-(2,2-Difluoroethoxy)nicotinaldehyde CAS 1698780-65-2
| CAS No. | 1698780-65-2 |
| Molecular Formula | C8H7F2NO2 |
| Molecular Weight | 187.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-(2,2-Difluoroethoxy)nicotinaldehyde (C8H7F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 187.14 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(2,2-Difluoroethoxy)nicotinaldehyde (CAS 1698780-65-2) is a high-purity analytical reference standard with the molecular formula C8H7F2NO2 and a molecular weight of 187.14 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2,2-Difluoroethoxy)nicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7F2NO2 |
| Molecular Weight | 187.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethoxy Standards
- 6-(2,2-Difluoroethoxy)nicotinaldehyde (CAS 1555510-04-7)
- 2-(2,2-difluoroethoxy)-4-methylaniline (CAS 1018053-48-9)
- 3-(2,2-Difluoroethoxy)-4-methylaniline (CAS 1183987-08-7)
- 2-(2,2-Difluoroethoxy)-6-methylaniline (CAS 1184255-71-7)
- (2-(2,2-Difluoroethoxy)phenyl)methanamine (CAS 937602-97-6)
- (4-(2,2-Difluoroethoxy)phenyl)methanamine (CAS 877151-57-0)
- 2-(2,2-Difluoroethoxy)-5-methylaniline (CAS 937603-00-4)
- 4-(2,2-Difluoroethoxy)-2-methylaniline (CAS 937602-96-5)
Recommended Standards
- 4-Amino-2,3-difluorophenyl acetate (CAS 162819-06-9)
- Methyl 2-amino-3,4-difluorobenzoate (CAS 170108-07-3)
- 2-(Difluoromethyl)-5-methylpyridine-3-carboxylic acid (CAS 1616240-29-9)
- 2-(Difluoromethyl)-6-methylnicotinic acid (CAS 1708178-67-9)
- (5E)-5-(3,4-Dichlorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 6326-22-3)
- 6-((4-Chlorophenyl)thio)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 339017-49-1)
- N-(2-chloropyrimidin-4-yl)acetamide (CAS 111049-96-8)
- 4-Pentyl-N-((3-(4-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)methyl)benzenesulfonamide (CAS 681213-48-9)
- 2,5-Dibromoselenophene (CAS 1755-36-8)
- Sodium 2-Naphthoate (CAS 17273-79-9)
- 4-Cyclopropoxy-N-methyl-5-(trifluoromethyl)picolinamide (CAS 1243392-38-2)
- 835617-36-2 Benzenesulfonic acid,2,4,6-trimethyl-, hydrate (1:2) CTK5F0846 (CAS 835617-36-2)
- 1-(3-Bromophenyl)azepane (CAS 1313883-57-6)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com