8-Methyl-2-(trifluoromethyl)quinolin-4-ol CAS 1701-19-5
| CAS No. | 1701-19-5 |
| Molecular Formula | C11H8F3NO |
| Molecular Weight | 227.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Methyl-2-(trifluoromethyl)quinolin-4-ol.
8-Methyl-2-(trifluoromethyl)quinolin-4-ol (CAS 1701-19-5) is a high-purity analytical reference standard with the molecular formula C11H8F3NO and a molecular weight of 227.18 g/mol.
Structurally, 8-Methyl-2-(trifluoromethyl)quinolin-4-ol (C11H8F3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 227.18 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Methyl-2-(trifluoromethyl)quinolin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8F3NO |
| Molecular Weight | 227.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 1-Methyl-7-(trifluoromethyl)quinolin-4(1H)-one (CAS 108494-53-7)
- (4-(Trifluoromethyl)quinolin-2-yl)methanol (CAS 1116339-56-0)
- 1-Methyl-8-(trifluoromethyl)quinolin-4(1H)-one (CAS 1209284-64-9)
- 6-Methyl-2-(trifluoromethyl)quinolin-4(1H)-one (CAS 123638-04-0)
- β-(Trifluoromethyl)-4-morpholinepropanoic acid (CAS 1343857-33-9)
- 1-(6-(Trifluoromethyl)-1H-indol-4-yl)ethanone (CAS 1352897-41-6)
- 5'-(Trifluoromethyl)-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one (CAS 1360898-86-7)
- 7'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indolin]-2'-one (CAS 1360931-90-3)
Recommended Standards
- (7-(Trifluoromethyl)quinolin-3-yl)methanol (CAS 1610696-37-1)
- 4-Hydroxy-6-methyl-2-(trifluoromethyl)quinoline (CAS 1701-20-8)
- n-(Tert-butyl)-n-(2,2,2-trifluoroacetyl)glycine (CAS 1536895-50-7)
- 8-Methyl-4-(trifluoromethyl)quinolin-2(1H)-one (CAS 1701-23-1)
- 3,6-bis(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine 685106-99-4 KS-000038J6 (CAS 685106-99-4)
- tert-Butyl 4-formyl-2-methylpiperidine-1-carboxylate (CAS 416852-38-5)
- 4-Chloro-2-[chloro(difluoro)-methoxy]-1-methyl-benzene (CAS 1404194-99-5)
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Why CATO?
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