| CAS No. | 1701-25-3 |
| Molecular Formula | C11H7ClF3N |
| Molecular Weight | 245.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 245.63 g/mol gives 4-Chloro-8-methyl-2-(trifluoromethyl)quinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-8-methyl-2-(trifluoromethyl)quinoline (CAS 1701-25-3) is a high-purity analytical reference standard with the molecular formula C11H7ClF3N and a molecular weight of 245.63 g/mol.
Based on its molecular formula C11H7ClF3N, 4-Chloro-8-methyl-2-(trifluoromethyl)quinoline contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 245.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C11H7ClF3N |
| Molecular Weight | 245.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |