4-Chloro-6-methyl-2-(trifluoromethyl)quinoline CAS 1701-26-4
| CAS No. | 1701-26-4 |
| Molecular Formula | C11H7ClF3N |
| Molecular Weight | 245.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Chloro-6-methyl-2-(trifluoromethyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Chloro-6-methyl-2-(trifluoromethyl)quinoline (CAS 1701-26-4), molecular formula C11H7ClF3N and molecular weight 245.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-6-methyl-2-(trifluoromethyl)quinoline (C11H7ClF3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H7ClF3N |
| Molecular Weight | 245.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-3-methyl-6-(trifluoromethyl)quinoline (CAS 1203578-79-3)
- 1-[3-Chloro-5-(trifluoromethyl)phenyl]cyclopropanecarbonitrile (CAS 1314773-42-6)
- 4-Chloro-3-methyl-2-(trifluoromethyl)quinoline (CAS 1344242-18-7)
- 8-Chloro-4-fluoro-3-hydroxy-7-methoxy-3,4-dihydroisoquinolin-1(2H)-one (CAS 1616288-69-7)
- 4-Chloro-8-methyl-2-(trifluoromethyl)quinoline (CAS 1701-25-3)
- N-{[2-chloro-3-(1,3-dioxolan-2-yl)-6-fluorophenyl]methylidene}hydroxylamine (CAS 1807888-07-8)
- 1-(2-Chloro-5-(trifluoromethyl)phenyl)-1H-pyrrole (CAS 383137-53-9)
- 1-(4-Chloro-3-(trifluoromethyl)phenyl)-1H-pyrrole (CAS 383137-92-6)
Recommended Standards
- 1-((3,5-Diamino-6-chloropyrazine-2-carbonyl)oxy)guanidine (CAS 70311-45-4)
- 3-(Chloromethyl)-7-(trifluoromethyl)quinoline (CAS 1610696-38-2)
- 2-Acetamido-2-(4-chloro-3-fluorophenyl)acetic acid (CAS 1343771-25-4)
- 1-[4-Chloro-2-(trifluoromethyl)phenyl]-1H-pyrrole (CAS 647824-83-7)
- 4-{5H,6H,7H,8H,9H-[1,2,4]triazolo[4,3-a]azepin-3-yl}aniline (CAS 109220-81-7)
- (2R,3R)-Pyrrolidine-2,3-dicarboxylic acid (CAS 131669-74-4)
- 2-(2-Phenoxyethyl)isoindoline-1,3-dione (CAS 83725-61-5)
- 3-(4-phenylphenyl)propanal (CAS 75677-09-7)
- 57368-07-7 2,2'-(Ethane-1,2-diyldiimino)bis((2-hydroxy-5-sulfophenyl)acetic acid) EC 611-514-5 (CAS 57368-07-7)
- (r)-2-((Tert-butoxycarbonyl)amino)-3-(3-methylpyridin-2-yl)propanoic acid (CAS 1354970-49-2)
- 7-Chloro-3-(3,4-dichlorophenyl)-1-((1-ethylpiperidin-3-yl)imino)-10-hydroxy-1,2,3,4-tetrahydroacridin-9(10H)-one (CAS 144128-42-7)
- 1-[3,5-Bis(trifluoromethyl)benzoyl]-3-methylpiperazine (CAS 1240567-35-4)
- 4-(5-Methylthiophen-2-yl)butan-2-amine (CAS 303070-17-9)
- D-[γ-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226254)
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