Gadobutrol Impurity 106 CAS 170454-90-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.170454-90-7
Molecular FormulaC10H22N4O2
Molecular Weight230.31 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Gadobutrol Impurity 106 CAS 170454-90-7 chemical structure

Description

The occurrence of Gadobutrol Impurity 106 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Gadobutrol Impurity 106 (CAS 170454-90-7), a pharmacopoeial impurity reference standard (molecular formula C10H22N4O2, MW 230.31 g/mol) used for the identification and quantification of trace impurities in APIs.

Gadobutrol Impurity 106 (C10H22N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H22N4O2
Molecular Weight230.31 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)2005
Nitrogen Atoms4

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