Gadobutrol Impurity 135 CAS 67705-42-4
| CAS No. | 67705-42-4 |
| Molecular Formula | C9H18N4 |
| Molecular Weight | 182.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Gadobutrol Impurity 135.
CATO supplies Gadobutrol Impurity 135 (CAS 67705-42-4), a pharmacopoeial impurity reference standard (molecular formula C9H18N4, MW 182.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C9H18N4, Gadobutrol Impurity 135 contains a nitrile group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 182.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Gadobutrol Impurity 135 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H18N4 |
| Molecular Weight | 182.27 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 4 |
Related Gadobutrol Standards
- Gadobutrol Impurity 148 (CAS CATO-C4X-2120148)
- Gadobutrol Impurity 54 (CAS CATO-C4X-2120154)
- Gadobutrol Impurity 48 (CAS 38361-85-2)
- Gadobutrol Impurity 11 (CAS 294-90-6)
- Gadobutrol Impurity 17 (CAS 127723-03-9)
- Gadobutrol Impurity 3 (CAS 1822607-61-3)
- Gadobutrol Impurity 44 (CAS 55403-02-6)
- Gadobutrol Impurity 111 (CAS 619-73-8)
Recommended Standards
- Triethoxyfluorosilane (CAS 358-60-1)
- Avatrombopag Impurity 54 (CAS 28989-50-6)
- n1-((1h-Imidazol-2-yl)methyl)-n3,n3-dimethylpropane-1,3-diamine (CAS 920478-78-0)
- 5-Pentylthiophene-2-carbaldehyde (CAS 100943-44-0)
- Orforglipron impurity 27 (CAS 465529-57-1)
- Tiamulin EP Impurity R(N-Benzyl-N,N-dibutylbutan-1-aminium chloride) (CAS 23616-79-7)
- Atrasentan Impurity 26 (CAS 1058401-84-5)
- 2,2,2-Trifluoro-N-(6-oxo-6-phenylhexyl)acetamide (CAS 39510-50-4)
- Flomoxef Impurity 40 (CAS CATO-C4X-138240)
- 1-(5-Chloro-1H-pyrrolo[3,2-b]pyridin-3-yl)ethan-1-one (CAS 1260384-24-4)
- (1R,2R)-1-amino-1-(thiophen-3-yl)propan-2-ol (CAS 1213044-43-9)
- Methyl 2-(3-chlorophenoxy)acetate (CAS 74411-14-6)
- 4-((2,5-Dichlorophenyl)amino)-2-(4-methylpiperazin-1-yl)-4-oxobutanoic acid (CAS 900011-70-3)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com