Donepezil Hydrochloride Monohydrate EP Impurity F CAS 172602-67-4
| CAS No. | 172602-67-4 |
| Molecular Formula | C24H27NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Donepezil Hydrochloride Monohydrate EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Donepezil Hydrochloride Monohydrate EP Impurity F (CAS 172602-67-4), a pharmacopoeial impurity reference standard (molecular formula C24H27NO3HCl, MW 413.94 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Donepezil Hydrochloride Monohydrate EP Impurity F (C24H27NO3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 413.94 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C24H27NO3 HCl |
| Molecular Weight | 413.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Donepezil Standards
- Donepezil Impurity 15 (CAS 1023500-88-0)
- Donepezil Impurity 44 (CAS 1026443-48-0)
- Donepezil Impurity 46 (CAS 1034439-43-4)
- Donepezil-d5 (CAS 1128086-25-8)
- Donepezil Impurity 55 (CAS 1189443-74-0 (free base))
- Donepezil Related Compound A HCl (CAS 120011-69-0)
- Donepezil Hydrochloride (CAS 120011-70-3)
- Donepezil Impurity 25 (CAS 120012-04-6)
Recommended Standards
- Luliconazole impurity 22 (CAS CATO-C4X-285322)
- Ezetimibe Impurity 61 (CAS CATO-C4X-109861)
- Venlafaxine Impurity 31 (CAS 1020719-35-0)
- (3-(2,4-Dichloro-5-fluorophenyl)-1-(o-tolyl)-1H-pyrazol-4-yl)methanol (CAS 618441-85-3)
- 1-(tert-Butylamino)-3,3-dimethylbutan-2-one hydrochloride (CAS 59288-29-8)
- 5,6,7,8-Tetrahydroisoquinoline-1-carbaldehyde (CAS 185220-65-9)
- Cyclopropyl(3-methyloxetan-3-yl)methanol (CAS 2090434-10-7)
- 2-Amino-1-(4-methoxybenzyl)-4,5-dimethyl-1H-pyrrole-3-carbonitrile (CAS 451485-75-9)
- N-[(pyridazin-3-yl)methyl]acetamide (CAS 1699949-28-4)
- 302798-54-5 (Leu31,Pro34)-Neuropeptide Y (13-36) (human, rat) MFCD00672463 (CAS 302798-54-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com