Atorvastatin Impurity 111 CAS 175453-07-3
| CAS No. | 175453-07-3 |
| Molecular Formula | C23H20N2O4 |
| Molecular Weight | 388.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Atorvastatin Impurity 111 (C23H20N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Atorvastatin Impurity 111 (CAS 175453-07-3), a pharmacopoeial impurity reference standard (molecular formula C23H20N2O4, MW 388.42 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H20N2O4 |
| Molecular Weight | 388.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 2 |
Related Atorvastatin Standards
- Atorvastatin Impurity 153 (CAS 444577-64-4)
- Atorvastatin Impurity 124 (CAS 666714-64-3)
- Atorvastatin Impurity 26 (CAS 444577-70-2)
- Atorvastatin Impurity 145 (CAS CATO-C4X-1132145)
- Atorvastatin Impurity 155 (CAS CATO-C4X-1132155)
- Atorvastatin Impurity 144 (CAS CATO-C4X-1132144)
- Atorvastatin Impurity 104 (CAS CATO-C4X-1132104)
- Atorvastatin Impurity 154 (CAS 1331869-19-2)
Recommended Standards
- Istradefylline impurity 30 (CAS CATO-C4X-106130)
- Terazosin EP Impurity B (CAS 1177261-73-2)
- Istradefylline Impurity 23 (CAS 187393-68-6)
- Irbesartan Impurity 10 (CAS 1312996-19-2)
- Leritrelvir impurity 1 (CAS CATO-C4X-34741)
- Nemonoxacin Impurity 38 (CAS CATO-C4X-312838)
- Moxifloxacin Impurity 34 (CAS 1797982-51-4)
- Phenylephrine Impurity 22 (CAS CATO-C4X-146722)
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- 9,10-Dihydrobenzo[a]pyrene (CAS 17573-15-8)
- 2-(Aminomethyl)-6-(difluoromethyl)-3-fluoropyridine-4-carboxaldehyde (CAS 1806990-09-9)
- 2-BROMO-2,2-DIFLUORO-1-ETHOXY-1-OXOETHANE 2-BROMO-2,2-DIFLUORO-1-ETHOXYETHAN-1-ONE 2-BROMODIFLUOROETHYLACETATE 667-27-6 BC004180 ETHYL 2-BROMO-2,2-DIFLUOROACETATE ETHYL BROMODIFLUOROACETATE (CAS 667-27-6)
- 5-Iodo-1H-indazole-6-carboxylic acid (CAS 1227270-92-9)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com