Atorvastatin Impurity 153 CAS 444577-64-4
| CAS No. | 444577-64-4 |
| Molecular Formula | C24H20FNO3 |
| Molecular Weight | 389.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Atorvastatin Impurity 153 (CAS 444577-64-4) is a certified pharmaceutical impurity reference standard with the molecular formula C24H20FNO3 and a molecular weight of 389.42 g/mol.
The molecular framework of Atorvastatin Impurity 153 (C24H20FNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Atorvastatin Impurity 153 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H20FNO3 |
| Molecular Weight | 389.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Atorvastatin Standards
- Atorvastatin Impurity 111 (CAS 175453-07-3)
- Atorvastatin Impurity 124 (CAS 666714-64-3)
- Atorvastatin Impurity 26 (CAS 444577-70-2)
- Atorvastatin Impurity 145 (CAS CATO-C4X-1132145)
- Atorvastatin Impurity 155 (CAS CATO-C4X-1132155)
- Atorvastatin Impurity 144 (CAS CATO-C4X-1132144)
- Atorvastatin Impurity 104 (CAS CATO-C4X-1132104)
- Atorvastatin Impurity 154 (CAS 1331869-19-2)
Recommended Standards
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- 4,7-Dihydroxy-2-methylquinoline-6-carboxylic acid (CAS 804435-49-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com