Clevidipine butyrate Impurity 21 CAS 175688-78-5
| CAS No. | 175688-78-5 |
| Molecular Formula | C20H20Cl2N2O4 |
| Molecular Weight | 423.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Clevidipine butyrate Impurity 21 (CAS 175688-78-5, C20H20Cl2N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Clevidipine butyrate Impurity 21 (C20H20Cl2N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Clevidipine butyrate Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H20Cl2N2O4 |
| Molecular Weight | 423.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Clevidipine Standards
- Clevidipine Impurity 36 (CAS CATO-C4X-101536)
- Clevidipine butyrate Impurity 7 (CAS 110962-94-2)
- Clevidipine Impurity 33 (CAS CATO-C4X-101533)
- Clevidipine Impurity 39 (CAS CATO-C4X-101539)
- Clevidipine butyrate Impurity 6 (CAS 175688-79-6)
- Clevidipine butyrate Impurity 4 (CAS 188649-48-1)
- Clevidipine Butyrate (CAS 167221-71-8)
- Clevidipine Butyrate impurity 20 (CAS 2458150-60-0)
Recommended Standards
- Baclofen impurity 73（E-Isomer） (CAS CATO-C4X-101273)
- Carboplatin Impurity 9 (CAS CATO-C4X-20619)
- Piperazine, 1,4-bis[(p-chlorophenoxy)acetyl]- (CAS 4190-83-4)
- tert-butyl N-(4-bromo-2-nitro-phenyl)-N-tert-butoxycarbonyl-carbamate (CAS 1228392-59-3)
- Calcitonin Impurity 16 (CAS CATO-C4X-221816)
- Anastrozole EP Impurity E (CAS 120511-88-8)
- Norepinephrine Impurity 12 (CAS CATO-C4X-151412)
- 2-(BROMOMETHYL)-6-METHYLPYRIDINE 6-(BROMOMETHYL)-2-METHYLPYRIDINE 6-METHYL-2-(BROMOMETHYL)PYRIDINE 68470-59-7 ABBYPHARMA AP-17-5766 BC004801 PYRIDINE, 2-(BROMOMETHYL)-6-METHYL- (CAS 68470-59-7)
- 1-benzyl-1,2,3,4-tetrahydroquinolin-6-amine dihydrochloride (CAS 1221723-21-2)
- 4-Hydroxy-N-(thiazol-2-yl)benzamide (CAS 94042-62-3)
- (1-(7-Methoxynaphthalen-1-yl)cyclopropyl)methanamine (CAS 1647055-48-8)
- 4-Bromoanisole (CAS 104-92-7)
- 4-(2,3-Dimethoxyphenyl)butan-1-ol (CAS 123014-49-3)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com