Cholecalciferol EP Impurity E CAS 17592-07-3
| CAS No. | 17592-07-3 |
| Molecular Formula | C27H44O |
| Molecular Weight | 384.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 384.64 g/mol gives Cholecalciferol EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Cholecalciferol EP Impurity E (CAS 17592-07-3), a pharmacopoeial impurity reference standard (molecular formula C27H44O, MW 384.64 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C27H44O, Cholecalciferol EP Impurity E contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 384.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H44O |
| Molecular Weight | 384.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
Related Cholecalciferol Standards
- trans-Cholecalciferol (CAS 1260149-80-1)
- Cholecalciferol EP Impurity A (CAS 22350-41-0)
- Cholecalciferol Impurity 15 (CAS 42607-12-5)
- Cholecalciferol EP Impurity B (CAS 434-16-2)
- Cholecalciferol EP Impurity C (CAS 5226-01-7)
- Cholecalciferol EP Impurity D (CAS 22350-43-2)
- Cholecalciferol-d6 (Vitamin D3-d6) (CAS 118584-54-6)
- Cholecalciferol Impurity 26 (CAS CATO-C4X-158626)
Recommended Standards
- Precalciferol (Previtamin D3) (CAS 1173-13-3)
- Cholesterol EP Impurity C (CAS 651-54-7)
- Cholesterol Impurity 17 (CAS 14214-69-8)
- 8-Dehydrocholesterol (CAS 70741-38-7)
- Decitabine Impurity 40 (CAS CATO-C4X-113740)
- Nemonoxacin Impurity 81 (CAS CATO-C4X-312881)
- Apremilast Impurity 55 (CAS 885268-06-4)
- 4-Methyl-d (CAS 94367-56-3)
- 3,3,4,4,5,5,6,6,6-Nonafluorohex-1-en-1-yl carbonate (CAS 1469980-27-5)
- a-Styrenylzinc bromide (CAS 151073-86-8)
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- (3-amino-1,1,1-trifluoro-2-methylpropan-2-yl)(benzyl)amine (CAS 1260983-07-0)
- Lixisenatide (CAS 320367-13-3)
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