8,8-Difluoro-1,4-dioxaspiro[4.5]decane CAS 176251-49-3
| CAS No. | 176251-49-3 |
| Molecular Formula | C8H12F2O2 |
| Molecular Weight | 178.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 8,8-Difluoro-1,4-dioxaspiro[4.5]decane (CAS 176251-49-3), a certified reference material (molecular formula C8H12F2O2, MW 178.18 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H12F2O2, 8,8-Difluoro-1,4-dioxaspiro[4.5]decane contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 178.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8,8-Difluoro-1,4-dioxaspiro[4.5]decane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12F2O2 |
| Molecular Weight | 178.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2007 |
| Halogen Content | F-containing |
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Recommended Standards
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- 3-(Pyridin-3-ylamino)cyclohex-2-enone (CAS 154152-62-2)
- Ammonium perchlorate (CAS 7790-98-9)
- 1-(4,4-Dimethylcycloheptyl)ethan-1-one (CAS 1507473-96-2)
- 2-isopropyl-4-(4-piperidyl)pyrimidine (CAS 1247142-15-9)
- (1R,2S)-2-methoxycyclopropanamine (CAS 2306254-32-8)
- 2-Hydroxypropyl decanoate (CAS 88357-29-3)
- 1-(3-Methoxy-5-methylphenyl)propan-1-one (CAS 29578-84-5)
- 4-(2-Chloroallyl)thiomorpholine-3-carboxylic acid (CAS 1544016-77-4)
- 1346597-98-5 |A-[(Diethyl-d10)amino]benzeneacetic Acid Ethyl Ester (CAS 1346597-98-5)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com