N-(6-Amino-3-methyl-2,4-dioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-dibutyl-4-hydroxybenzamide CAS 176370-46-0
| CAS No. | 176370-46-0 |
| Molecular Formula | C27H34N4O4 |
| Molecular Weight | 478.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(6-Amino-3-methyl-2,4-dioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-dibutyl-4-hydroxybenzamide.
CATO supplies N-(6-Amino-3-methyl-2,4-dioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-dibutyl-4-hydroxybenzamide (CAS 176370-46-0), a certified reference material (molecular formula C27H34N4O4, MW 478.58 g/mol) for analytical method development and quality control.
The molecular framework of N-(6-Amino-3-methyl-2,4-dioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-dibutyl-4-hydroxybenzamide (C27H34N4O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(6-Amino-3-methyl-2,4-dioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-dibutyl-4-hydroxybenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H34N4O4 |
| Molecular Weight | 478.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2007 |
| Nitrogen Atoms | 4 |
Related N Standards
- N-(6-Amino-3-methyl-2,4-dioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidin-5-yl)-3,5-di-tert-butyl-4-hydroxybenzamide (CAS 176378-80-6)
- N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2-Deoxyguanosine (CAS 142038-30-0)
- (8E)-2-Amino-4-[2-(trifluoromethyl)phenyl]-8-{[2-(trifluoromethyl)phenyl]methylidene}-4H,5H,7H,8H-pyrano[3,2-c]pyran-3-carbonitrile (CAS 445390-77-2)
- 6-Amino-4-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-yl}-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyrimidin-2-one (CAS 338965-02-9)
- 6-Amino-7-((4-chlorophenyl)sulfonyl)-5-(4-ethoxyphenyl)-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitrile (CAS 691396-68-6)
- 4-Amino-N-(1-((3-chloro-2-fluorophenyl)amino)-6-methylisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide (CAS 1446113-23-0)
- 4-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-2-hydroxybutyl tetrahydrogen triphosphate (CAS 108491-46-9)
- 2-Amino-9-(5-((6-chloro-2-methoxyacridin-9-yl)amino)pentyl)-1H-purin-6(9H)-one (CAS 103083-41-6)
Recommended Standards
- 1,3-Di(pyren-1-yl)benzene (CAS 1644438-20-9)
- 1,3-Bis[5-(4-tert-butylphenyl)-2-[1,3,4]oxadiazolyl]benzene (CAS 138372-67-5)
- (2S,4S)-1-Boc-4-(4-benzyl-1-piperazinyl)-2-(3,3-difluoropyrrolidine-1-carbonyl)pyrrolidine (CAS 1864002-93-6)
- Di-tert-butyl 4,4'-(pyrimidine-4,6-diylbis(oxy))bis(piperidine-1-carboxylate) (CAS 1353989-70-4)
- tert-Butyl 2-oxa-5,8-diazaspiro[3.5]nonane-5-carboxylate (CAS 1367936-05-7)
- α-Hydroxybenzylphosphinic Acid Sodium Salt (CAS 7492-18-4)
- 3-Amino-1-methyl-3,4-dihydroquinolin-2(1H)-one (CAS 403860-64-0)
- Tert-butyl 4-(amino(phenyl)methyl)piperidine-1-carboxylate (CAS 612532-09-9)
- 4-Bromo-6-(trifluoromethoxy)benzene-1,3-diamine (CAS 1373233-29-4)
- 5-(Hydroxymethyl)-4-(((2-(5-methoxy-1H-indol-3-yl)ethyl)imino)methyl)-2-methylpyridin-3-ol (CAS 98497-90-6)
- Palladium, [1,3-bis[2,6-bis(1-methylethyl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene]dichloro(quinoline)-, (SP-4-1)- (CAS 1872204-31-3)
- 3-Methyl-1-pyridin-2-yl-1H-pyrazol-5-ol (CAS 38695-92-0)
- 3-Bromo-2-(methoxymethoxy)phenylboronic acid (CAS 1431330-19-6)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
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