(8E)-2-Amino-4-[2-(trifluoromethyl)phenyl]-8-{[2-(trifluoromethyl)phenyl]methylidene}-4H,5H,7H,8H-pyrano[3,2-c]pyran-3-carbonitrile CAS 445390-77-2
| CAS No. | 445390-77-2 |
| Molecular Formula | C24H16F6N2O2 |
| Molecular Weight | 478.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(8E)-2-Amino-4-[2-(trifluoromethyl)phenyl]-8-{[2-(trifluoromethyl)phenyl]methylidene}-4H,5H,7H,8H-pyrano[3,2-c]pyran-3-carbonitrile (CAS 445390-77-2) is a high-purity analytical reference standard with the molecular formula C24H16F6N2O2 and a molecular weight of 478.39 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (8E)-2-Amino-4-[2-(trifluoromethyl)phenyl]-8-{[2-(trifluoromethyl)phenyl]methylidene}-4H,5H,7H,8H-pyrano[3,2-c]pyran-3-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 478.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (8E)-2-Amino-4-[2-(trifluoromethyl)phenyl]-8-{[2-(trifluoromethyl)phenyl]methylidene}-4H,5H,7H,8H-pyrano[3,2-c]pyran-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H16F6N2O2 |
| Molecular Weight | 478.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 1-(4-Methoxybenzyl)-3-(((4-methoxybenzyl)oxy)methyl)-5-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2489244-20-2)
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