Clonazepam Impurity 5 CAS 17714-02-2
| CAS No. | 17714-02-2 |
| Molecular Formula | C15H12ClN3O4 |
| Molecular Weight | 333.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Clonazepam Impurity 5.
As a process- or degradation-related impurity, Clonazepam Impurity 5 (CAS 17714-02-2, C15H12ClN3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Clonazepam Impurity 5 (C15H12ClN3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Clonazepam Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12ClN3O4 |
| Molecular Weight | 333.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Clonazepam Standards
- Methyl Clonazepam (CAS 5527-71-9)
- Clonazepam impurity 11 (CAS CATO-C4X-140311)
- Clonazepam impurity 14 (CAS CATO-C4X-140314)
- Clonazepam impurity 10 (CAS CATO-C4X-140310)
- 【禁售不询】Clonazepam (CAS 1622-61-3)
- Clonazepam EP Impurity B (CAS 55198-89-5)
- Clonazepam Impurity 3 (CAS 180854-85-7)
- Clonazepam Impurity 20 (CAS CATO-C4X-140320)
Recommended Standards
- 1-(6-Chloropyridin-2-yl)-4-(1H-1,2,4-triazol-1-yl)-1H-pyrazol-5-yl dimethylcarbamate (CAS 955975-72-1)
- Penfluridol Impurity 3 (CAS CATO-C4X-35383)
- 4-(4-Chloro-6-methoxy-3-nitroquinolin-7-yl)-3,5-dimethylisoxazole (CAS 1300031-65-5)
- ((5-Carboxy-2-chlorophenyl)sulfonyl)proline (CAS 1008580-51-5)
- Sulfadimethoxine Impurity (CAS 69943-39-1)
- Glycopyrronium Bromide EP Impurity N Bromide (CAS 58493-54-2)
- Albendazole impurity 30 (CAS CATO-C4X-153530)
- Ozagrel (CAS 82571-53-7)
- Ethyl 2-((2-phenyl-6-((phenylthio)methyl)pyrimidin-4-yl)thio)acetate (CAS 303147-67-3)
- trans-4-(4-methylpiperazin-1-yl)cyclohexan-1-amine (CAS 883195-08-2)
- Prilocaine EP Impurity C (CAS 42459-37-0)
- Methyl 2-(4-(4-bromophenyl)-1H-pyrazol-1-yl)acetate (CAS 1351382-69-8)
- (1-(Cyclopropylmethyl)-1H-imidazol-5-yl)methanol (CAS 497855-92-2)
- Peptide 434 (CAS CATO-CPTD788434)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com