Clonazepam EP Impurity B CAS 55198-89-5
| CAS No. | 55198-89-5 |
| Molecular Formula | C15H10ClN3O3 |
| Molecular Weight | 315.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Clonazepam EP Impurity B (CAS 55198-89-5) is a certified pharmaceutical impurity reference standard with the molecular formula C15H10ClN3O3 and a molecular weight of 315.71 g/mol.
Structurally, Clonazepam EP Impurity B (C15H10ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 315.71 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Clonazepam EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10ClN3O3 |
| Molecular Weight | 315.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Clonazepam Standards
- 【禁售不询】Clonazepam (CAS 1622-61-3)
- Methyl Clonazepam (CAS 5527-71-9)
- Clonazepam Impurity 5 (CAS 17714-02-2)
- Clonazepam impurity 11 (CAS CATO-C4X-140311)
- Clonazepam impurity 14 (CAS CATO-C4X-140314)
- Clonazepam Impurity 21 (CAS 4306-32-5)
- Clonazepam impurity 10 (CAS CATO-C4X-140310)
- Clonazepam Impurity 3 (CAS 180854-85-7)
Recommended Standards
- Metoclopramide impurity 77 (CAS CATO-C4X-141577)
- (4-Chlor-2-nitro-phenyl)-malonsaeure-diaethylester (CAS 10565-16-9)
- Regadenoson Impurity 34 (CAS 13406-50-3)
- N'-[(tert-Butoxy)carbonyl]-2-chloro-4-nitrobenzohydrazide (CAS 2055119-26-9)
- Vonoprazan Impurity 199 (CAS CATO-C4X-1020199)
- Clindamycin Impurity 22 HCI (CAS 1123211-70-0（free base）)
- Etoricoxib Impurity 49 (CAS 73312-69-3)
- 3,4-Dichloro-5-fluoropyridine (CAS 851179-02-7)
- N-(1-Isopropyl-5-pyrazolyl)-N’-methylfuran-2-carboximidamide (CAS 1006463-47-3)
- tert-Butyl ((1-(2-aminoethyl)pyrrolidin-3-yl)methyl)carbamate (CAS 173340-52-8)
- 2-[(4-Methylphenyl)methanesulfinyl]-4-(morpholin-4-yl)-5,6,7,8-tetrahydroquinazoline (CAS 477714-05-9)
- (R)-Benzyl 3-(2-amino-N-methylacetamido)pyrrolidine-1-carboxylate (CAS 1353996-06-1)
- 6-(Difluoromethyl)-3-fluoro-2-hydroxyisonicotinonitrile (CAS 1806948-34-4)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com